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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 January, 1987
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
no
GLP compliance:
no
Specific details on test material used for the study:
Test material identified as: FAT 45082/E
Analytical monitoring:
no
Details on sampling:
None
Vehicle:
not specified
Details on test solutions:
None
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Details on test organisms:
None
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Post exposure observation period:
None
Hardness:
None
Test temperature:
23 °C
pH:
8.2
Dissolved oxygen:
7.6 - 7.8
Salinity:
None
Nominal and measured concentrations:
300 and 1000 mg/L (nominal)
Details on test conditions:
None
Reference substance (positive control):
not specified
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC100
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
No mortality seen at any of the exposure concentrations.
Results with reference substance (positive control):
None
Reported statistics and error estimates:
None
Sublethal observations / clinical signs:

None

Validity criteria fulfilled:
not specified
Conclusions:
LC50 of FAT 45082/E in this fish acute toxicity test was determined to be >1000 mg/L.
Executive summary:

An acute fish toxicity test was performed according to equivalent or similar as OECD Guideline 203. Zebra fish were used in this test. Two groups each containing 10 fish, were exposed to test concentrations of 300 and 1000 mg/L. No mortality was observed throughout the exposure period of 96 hours. Hence, based on the findigs of the study, the LC50 of FAT 45082/E in this fish acute toxicity test was determined to be >1000 mg/L.

LC0 (48 h): >1000 mg/L

LC0 (96 h): >1000 mg/L

LC50 (48 h): >1000 mg/L

LC50 (96 h): >1000 mg/L

LC100 (48 h): >1000 mg/L

LC100 (96 h): >1000 mg/L

Description of key information

Vat Black 065 is regarded to have low toxicity to fish, with 96h LC50 >1000 mg/l.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information

The toxicity of target chemical was evaluated in three acute studies with similar methodology that is equivalent to OECD Guideline 203. Two groups of 10 Zebra fish each were exposed to test concnetrations of 300 and 1000 mg/l till 96 hours. No mortality was in any of the studies. Based on the findings of the studies, following results were obtained:

LC0 (48 & 96 h): >1000 mg/l

LC50 (48 & 96 h): >1000 mg/l

LC100 (48 & 96 h): >1000 mg/l

TL0 (48 & 96 h): >1000 mg/l

TL50 (48 & 96 h): >1000 mg/l

TL100 (48 & 96 h): >1000 mg/l

The LC50 values from key and supporting studies suggests that FAT 45082 is non-toxic to fish.