Registration Dossier
Registration Dossier
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EC number: 434-630-6 | CAS number: 60372-77-2
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- L-Arginine, N2-(1-oxododecyl)-, ethyl ester, hydrochloride (1:1)
- Type of composition:
- legal entity composition of the substance
- State / form:
- solid: particulate/powder
- Related composition:
- L-Arginine, N2-(1-oxododecyl)-, ethyl ester, hydrochloride (1:1)
- Reference substance:
- L-Arginine, N2-(1-oxododecyl)-, ethyl ester, hydrochloride (1:1)
- Name:
- L-Arginine, N2-(1-oxododecyl)-, ethyl ester, hydrochloride (1:1)
- Type of composition:
- boundary composition of the substance
- State / form:
- solid: particulate/powder
- Reference substance:
- L-Arginine, N2-(1-oxododecyl)-, ethyl ester, hydrochloride (1:1)
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Persistence Assessment
Evidence of ready biodegradation:
Study report: The substance is biodegradable is readily biodegradable. The biodegradation of the substance was 89% in 29 days.
(Guideline 301B).
The substance is not fulfilling the criteria for Persistence (P)
Bioaccumulation Assessment
The log Kow value of the substance is lower than 4.5: The mean value for the partition coefficient of Nα-Lauroyl-L-arginine ethyl ester monohydrochloride (LAE) was log Pow=1.43
(Guideline OECD 107).
The substance is not fulfilling the criteria for Bioaccumulation (B)
Toxicity Assessment
There is no long-term toxicity studies available with fish and daphnia.
- Short-term toxicity to fish: Key study: LC50 (96h) = 8.36 mg/L (based on mortality) (
Guideline OECD 203).
- Short-term toxicity to aquatic invertebrates: Key study: EC50 (48h) = 6.54 mg/L , NOAEL 4.0mg/L (based on mobility)
(Guideline OECD 202)
- Toxicity to aquatic algae: Key study: EC50 (72h) = 0.723 mg/L and NOEC (72h) = 0.243 mg/L (based ongrowth rate)
(Guideline OECD 201)
There is no evidence of CMR.
Not classified for specific target organ toxicity after repeated exposure.
The substance is not fulfilling the criteria for Toxicity (T)
Conclusion:The substance is determined to be not PBT/vPvB.
Referenceopen allclose all
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