Registration Dossier
Registration Dossier
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EC number: 274-503-0 | CAS number: 70247-74-4
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to fish, invertebrates, aquatic plants and microorganisms was investigated.
Additional information
Short-term toxicity tests are available for all the three tropic levels (fish, invertebrates, aquatic plants and microorganisms). In an 48 h acute fish toxicity test, the test substance FAT 20035 was observed to have 48 h TL50 to Zebrafish 6.3 mg/L. 48 h EC50 value of FAT 20035 to Daphnia magna was noted to be >100 mg/L. IC50 (3h) of FAT 20035 is >100 mg/l for microorganisms.
The test material FAT 20035 is a dark color dye which when mixed in test medium will impart dark color. Due to light absorption, colored substances such as dyes can inhibit algal growth, which is not the result of a toxic action. This shading effect can confound measures of chemical toxicity and thus impair the risk assessment. In an effort to avoid this problem Lemna gibba (Duckweed) Growth Inhibition test (Static) is conducted. In a GLP compliant OECD 221 guideline study Lemna gibba (Duckweed) exposed to the test item FAT 20035 recorded:
7 day ErC50 of test substance based upon the frond number (growth rate) is 86.90 mg/L (89.83 - 84.06 mg/L) while,
7 day EyC50 based upon the frond number is 51.84 mg/L (53.04 - 50.68 mg/L).
7 day ErC50 based upon the frond dry weight (growth rate) is 87.38 mg/L (90.33 - 84.52 mg/L).
7 day EyC50 based upon the frond dry weight is 51.08 mg/L (52.24 - 49.95 mg/L).
Based on these results the test substance FAT 20035 can be regarded as toxic to aquatic species.
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