Registration Dossier
Registration Dossier
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EC number: 229-142-3 | CAS number: 6417-83-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- The rationale to read across the data is attached in Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 102 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: the EC10 is > maximum solubility in medium
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: the EC50 is > maximum solubility in medium
- Duration:
- 72 h
- Dose descriptor:
- EC90
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- - Appearance of the test media: no remarkable observations, clear test medium
- Unusual cell shape: none
- Unusual cell size: none - Validity criteria fulfilled:
- yes
- Conclusions:
- Calcium 4-[(5-chloro-4-methyl-2-sulfonatophenyl)diazenyl]-3-hydroxy-2-naphthoate is with high probability not acutely harmful to aquatic algae. No toxic effects occur within the range of solubility. This result is read across to the registered substance.
Reference
Description of key information
The test item is with high probability not acutely harmful to aquatic algae. No toxic effects occur within the range of solubility.
Key value for chemical safety assessment
Additional information
The effect of the read-across (CAS 7023-61-2) substance on the growth of Pseudokirchnerella subcapitata was investigated in a study following GLP and OECD guideline 201. Due to the low solubility of the read-across substance a water accommodated fraction has been tested. The algae were exposed for 72 hours to the test substance. Based on the algal growth rate an EC50 and EC10 >100 mg/l were determined (BASF SE, 2007).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
