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Diss Factsheets
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EC number: 205-769-8 | CAS number: 150-76-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Four data are referenced for terrestrial toxicity:
- toxicity to soil macroorganisms: Hartenstein (1982, reliability 3) measured the growth rate and mortality of Eisenia foetida after 2 weeks of exposure with the test substance in activated sludge. A 42 day LC100= 40 g/kg soil dry weight (4% w/w reported in the publication) was calculated based on nominal test material concentration, for mortality effect, and a 42 day LOEC= 10 g/kg dry weight (1% w/w reported) was calculated based on nominal test material concentration, for growth rate.
- toxicity to terrestrial plants: Wang et al. in 2002 (reliability 3) measured by a filter paper contact method the seed germination of Cucumis sativus when PMP is applicated for 2 days. The resulting 2 day EC50 was 229.3 mg/L based on nominal test material concentration.
- toxicity to birds: Schafer and Jacobson in 1983 (reliability 3) carried out an acute oral toxicity on Agelaius phoeniceus (red- winged blackbird). The measured LD50 was > 113 mg/kg bw.
- toxicity to frogs: Wang et al. in 2001 (reliability 2) investigated the PMP toxicity on frog tadpoles. The study was conducted in semi static conditions, in freshwater, the exposure duration was 24 hours. No mortality occurred in the control. The resullting 24h LC50 was 294 mg/L.
Additional terrestrial tests are not required since mequinol is not supposed to be directly applied to soil and an indirect exposure to soil via sewage sludge transfer is unlikely since the substance is readily biodegradable. For such a substance, it can be assumed that it will be biodegraded within the STP process and as a consequence a transfer to the soil compartment is not expected. Furthermore, since Mequinol is neither adsorptive (log Koc = 1,74) nor bioaccumulative (log Kow = 1,3), a significant distribution into the soil compartment and a significant exposure of terrestrial organisms is not expected. Hence, information about effects on terrestrial organisms is not required and the equilibrium partitioning method is used for assessing the hazard to terrestrial organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.