Registration Dossier
Registration Dossier
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EC number: 406-880-6 | CAS number: 88917-22-0 ACETATE DPMA ACROSOLV; ACROSOLV DPMA ACETAT; ACROSOLV DPMA ACETATE; DOWANOL DPMA; DOWANOL DPMA GLYCOL ETHER; DOWANOL DPMA GLYKOL ETHER; ETHER DE GLYCOL DPMA DOWANOL
Endpoint summary
Administrative data
Description of key information
Additional information
Acute toxicity studies have been conducted in fish, daphnia and algae. In summary, for the aquatic compartment dipropylene glycol methyl ether acetate shows EC50s/LC50s that exceed 1000 mg/l in daphnia (48 hr) and algae (72 hr). The LC50 (96 hr) for fish was greater than 100 mg/l.
An activated sludge respiration inhibition test showed an EC50 greater than 1000 mg/l for micro-organisms.
Dipropylene glycol methyl ether acetate is classified as inherently biodegradable meeting the specific criteria. Therefore, ultimate biodegradation is expected in freshwater. The risk assessment shows that the PEC/PNEC ratio is clearly < 1 in surface water, indicating no need for further information or testing. According to REACH Annex IX requirements, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigations. Hence, long-term testing in aquatic species (fish and daphnia magna) can be waived for dipropylene glycol methyl ether acetate.
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