Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 269-665-4 | CAS number: 68308-74-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72-hour EL50 for growth rate was found to be >32 mg/L, and the NOEC was found to be 0.32 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 32 mg/L
- EC10 or NOEC for freshwater algae:
- 0.32 mg/L
Additional information
OECD 201 algal studies are available for DMATO and Busperse 2422, which contains DMATO at 15%.
In the OECD 201 study for DMATO Pseudokirchneriella subcapitata was exposed to the water accommodating fraction (WAF) of the substance due to its low solubility and complex nature. After 72 hours exposure the EL50 for growth rate was determined to be >32 mg/L and the NOEC was determined to be 0.32 mg/L. As the toxicological effects could not be attributed to a single component or components within the mixture, the effect concentrations are given in terms of nominal concentrations of the test substance.
In the study conducted with Busperse 2422 the 72-h ErC50-value (72 h) was calculated to be 3.5 mg/L based on the fluorescence measurements. The NOEC was statistically determined to be 0.62 mg/L.
Although the EC50 value determined for Busperse 2422 is lower than that of DMATO, it is considered appropriate to use the higher value from the DMATO study as Busperse 2422 only contains DMATO at approximately 15% and as the study for DMATO is considered to be of a higher quality. As such it is considered more appropriate to use the values from the study conducted with pure DMATO for risk assessment purposes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
