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EC number: 266-946-3 | CAS number: 67701-28-4 This substance is identified by SDA Substance Name: C8-C18 and C18 unsaturated trialkyl glyceride and SDA Reporting Number: 01-001-00.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From Jan. 25, 2010 to March 5, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study was conducted according to standard guidelines (with GLP)
- Justification for data waiving:
- other:
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes
- Type of method:
- column elution method
Test material
- Reference substance name:
- Glycerides, C8-18 and C18-unsatd.
- EC Number:
- 266-946-3
- EC Name:
- Glycerides, C8-18 and C18-unsatd.
- Cas Number:
- 67701-28-4
- Molecular formula:
- Triglycerides containing a glycerol backbone esterified to fatty acids with a carbon chain length of C8-18 as well as unsaturated C18 fatty acids
- IUPAC Name:
- Tri(C8-18 and C18-unsatd. fatty acyl)glycerol
- Details on test material:
- - Name of test material (as cited in study report): Fully hydrogenated coconut oil (CAS N° 84836-98-6, EC N° 284-283-8); under the SDA nomenclature, the name of this substance is ‘Glycerides, C8-18, C18 unsaturated’
- Physical state: Solid (bright yellow)
- Expiration date of the lot/batch: December 26, 2009
- Storage condition of test material: In original container, at room temperature (10-30 °C), in the dark
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- < 6.8 mg/L
- Temp.:
- 20 °C
- pH:
- >= 7 - <= 7.1
- Remarks on result:
- other: the water solubility was estimated to be below the limit of quantification
- Details on results:
- - Calibration range: 1 to 20 mg carbon/L pure water in the case of TC-calibration; 1 to 20 mg carbon/L pure water in the case of IC-calibration.
- Linearity of response: Correlation of peak area of different standard solutions with their corresponding concentrations, using a linear regression.
- Regression coefficient (r²): At least 0.999 in the case of TC; at least 0.998 in the case of IC
- Typical calibration curve: y = 4.278* x + 2.2242 in the case of TC; y = 4.232* x – 0.239 in the case of IC
- LOD TC: 0.900 mg carbon/L
- LOD IC: 1.392 mg carbon/L
- LOQ TC: 3.149 mg carbon/L
- LOQ IC: 4.772 mg carbon/L
The limit of quantification TOC (LOQ TOC) was determined as the lowest fortification level at which acceptable mean recovery (70 to 110% of nominal) with a relative standard deviation (RSD) <20% was obtained. The fortified samples were prepared with TC standard solutions in an additional TOC-analysis.
- LOQ TOC: 5 mg carbon/L
- Mean recovery in the fortified samples: 96 % (n = 9, RSD 1 %)
The water solubility of the test item was estimated to be below the limit of quatification of the analytical method.
Any other information on results incl. tables
None
Applicant's summary and conclusion
- Conclusions:
- The water solubility of fully hydrogenated coconut oil was estimated to be below the limit of quantification of the analytical method and was determined to be < 6.8 mg/L at 20 ± 2 °C.
- Executive summary:
The water solubility of fully hydrogenated coconut oil was determined using the coloumn elution method according to OECD Guideline 105 and EU Method A.6 with GLP compliance.
The test flasks, containing carrier material loaded with the test item solution, fully hydrogenated coconut + tetrahydrofuran (which was later removed by rotary evaporator), were stored in darkness at ambient temperature until the test was started. The carrier material was later poured into a coloumn (together with distilled water) which was connected to a pump. In the first experiment the coloumn flow was adjusted to 0.4 mL/min and in the second experiment the flow rate was adjusted to 0.2 mL/min.
The saturation concentration was estimated using the TOC-method.
The water solubility of fully hydrogenated coconut oil was estimated to be below the limit of quantification of the analytical method and was determined to be < 6.8 mg/L at 20 ± 2 °C.
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