Registration Dossier
Registration Dossier
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EC number: 200-875-0 | CAS number: 75-50-3
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21 -d EC10 was determined to be 3.9 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3.9 mg/L
Additional information
An EC50 (21 d) value of 14 mg/L and a NOEC (21 d) value of 8 mg/L were determined for Trimethylamine by the Ministry of the Environment of Japan.
The data of the original report were re-evaluated using ToxRat v2.10 in order to obtain an EC10, which is not originally reported. According to REACH Guidance document chapter R.10 Table R.10-1 (Overview of toxicity test endpoints and guidance on derivation of L(E)C50 and NOEC values) an EC10 for a long-term test which is obtained using an appropriate statistical method (usually regression analysis) will be used preferentially. The EC10 (21 d) was calculated to be 3.9 mg/L.
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