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Diss Factsheets
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EC number: 700-455-1 | CAS number: 380843-75-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 27 July 2009 - 23 September 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- yes
- Remarks:
- TGA sample pan was used to hold the sample horizontally
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- not specified
- Type of method:
- other: By calculation according OECD Test Guidance 104
Test material
- Reference substance name:
- 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
- EC Number:
- 700-455-1
- Cas Number:
- 380843-75-4
- Molecular formula:
- C26H29Cl2N5O3
- IUPAC Name:
- 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
- Details on test material:
- Equipment
Thermogravimetric Analyzer: TA Instrument Q 500 TGA
50ul Platinum sample pans: TA Instrument 952018.908
Temperature Calibration point Standards
Indium: Source: NIST; Certified Melting Temp.: 156.61ºC
Tin: Source: NIST Certified Melting Temp.: 231.95ºC
Vapour Pressure Reference Materials
n-Tricosane purity: 99.2%; Source: Chem Service; Lot: 309-98A
n-Hexacosane purity: 99.2%; Source: Chem Service; Lot: 209-53B
Benzophenone purity: 99.+%; Source: Acros Organics; Lot: AO240266
Constituent 1
Results and discussion
Vapour pressureopen allclose all
- Temp.:
- ca. 20 °C
- Remarks on result:
- other: The vapour pressure could not be determined for technical reasons, as the sample was thermally unstable at temperatures required to determine an evaporation rate by isothermal thermogravimetry.
- Temp.:
- ca. 20 °C
- Vapour pressure:
- < 0 Pa
- Remarks on result:
- other: Using the calculation method described in OECD Test Guidance 104
- Temp.:
- ca. 20 °C
- Vapour pressure:
- < 0 Pa
- Remarks on result:
- other: Using the US EPA software MPBPWIN v. 1.43 (the modified Grain Method)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.