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Diss Factsheets
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EC number: 203-809-9 | CAS number: 110-86-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Pyridine has been determined to be readily biodegradable, as shown by the results of the Guideline 301A test conducted by Gerike and Fischer (1979), who reported 91% DOC removal in 19 days, although this test did not specifically show that pyridine biodegradation met the criterion for 70% DOC removal within the 10-day window . In addition, Gerike and Fischer (1979) reported 58% theoretical CO2 evolution and 97% DOC removal in a Guideline 301B test, and reported 97% DOC removal in six days by Guideline 302B. Therefore, pyridine has been determined to be readily biodegradable, but failing the 10-day window.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
Pyridine has been shown to be readily biodegradable in the environment, as shown by the results of the Guideline 301A test conducted by Gerike and Fischer (1979); this test showed 91% DOC removal in 19 days, although this test did not specifically show that pyridine biodegradation met the criterion for 70% DOC removal within the 10-day window for ready biodegradability. However, other evidence from Gerike and Fischer (1979) supports extensive biodegradation within the 10-day window, including the reported 58% theoretical CO2 evolution and 97% DOC removal in a Guideline 301B test, and reported 97% DOC removal in six days by Guideline 302B. In a non-guideline study, Stoban et al.(2008) reported 100% biodegradation of 30 mM pyridine and 70mM pyridine in 5 days and 10 days, respectively, by the actinomycete Gordonia terrea. Ruffo et al.(1983) reported 94% biodegradation (CO2evolution) in 8 days by a modified Sturm test. In a non-guideline study, Cassidy et al.(1988) reported 100% biodegradation of 0.2 mg pyridine/L in 4 days and 100% biodegradation of 20 mg pyridine/L in 8 days (by TOC removal). In a non-guideline study, Leeet al.reported 100% biodegradation of 1.88 mM pyridine in 7 days by Pseudonocardia sp. strain M43 (test material analysis). Therefore, although pyridine has been determined to be readily biodegradable but failing the 10-day window, evidence from other tests indicates the likelihood that pyridine may be extensively biodegraded within a period of time less than 10 days.
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