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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
other: summary
Rationale for reliability incl. deficiencies:
other: Literature summary of additional toxicological information on MBT

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
The structural basis of the mutagenicity of chemicals in Salmonella thyphimurium: the National Toxicology Program Data Base
Author:
Rosenkranz, H., S.
Year:
1990
Bibliographic source:
Mutation Research, 228, 51-80
Reference Type:
publication
Title:
Induction of forward mutations at the thymidine kinase locus of mouse lymphoma cells: evidence for electrophilic and non-electrophilic mechanisms
Author:
Henry, B.; et al.
Year:
1998
Bibliographic source:
Mutation Research 397, 313-335
Reference Type:
publication
Title:
In vitro prediction of carcinogenicity using a bovine papillomavirus DNA-carrying C3H/10T1/2 cell line (T1)
Author:
Kowalski, L., A.; et al.
Year:
2001
Bibliographic source:
Environmental and Molecular Mutagenesis, 37, 231-240
Reference Type:
publication
Title:
The metabolic orgin of the sufur atom in the sulfhydryl group of 2-thiobenzothiazole metabolites derived from benzothiazyl sulfenamide in the rat
Author:
Fukuoka, M.; et al.
Year:
1987
Bibliographic source:
Arch. Toxicol. 61, 158-160
Reference Type:
publication
Title:
Human health risk assessment of 2-mercaptobenzothiazole in drinking water
Author:
Whittaker, M., H.
Year:
2004
Bibliographic source:
Toxicology and Industrial Health 20, 149-163
Reference Type:
publication
Title:
Electrophilic Chemistry Related to Skin Sensitization. Reaction Mechanistic Applicability Domain Classification for a Published Data Set of 106 Chemicals Tested in the Mouse Local Lymph Node Assay
Author:
Roberts, D.W. et al.
Year:
2007
Bibliographic source:
Che. Res. Toxicol. 20, 44-60
Reference Type:
publication
Title:
The guinea-pig skin sensitization test revisited: an evaluation formula to predict possible sensitization levels for eight chemicals used in household products
Author:
Momma, J. et al.
Year:
1998
Bibliographic source:
Toxicology 126, 75-82
Reference Type:
publication
Title:
Oxidation of 2-Mercaptobenzothiazole in Latex Gloves and Its Possible Haptenation Pathway
Author:
Chipinda, I. et al.
Year:
2007
Bibliographic source:
Chem. Res. Toxicol. 20, 1084-1092

Materials and methods

Type of study / information:
Literature summary of additional toxicological information on MBT
Principles of method if other than guideline:
other: Literature summary of additional toxicological information on MBT

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzothiazole-2-thiol
EC Number:
205-736-8
EC Name:
Benzothiazole-2-thiol
Cas Number:
149-30-4
Molecular formula:
C7H5NS2
IUPAC Name:
1,3-benzothiazole-2-thiol
Details on test material:
MBT

Results and discussion

Any other information on results incl. tables

Literature summary of additional toxicological information on MBT

Applicant's summary and conclusion