Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 269-103-8 | CAS number: 68187-51-9 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77496.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- Standard water pH 8 ISO 6341 OECD TGD 29
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- < 1 µg/L
- Temp.:
- 20 °C
- pH:
- 8
- Conclusions:
- Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
A very low water solubility was determined according to OECD Guideline 105. With a loading of 10 g zinc ferrite to water at pH 8 the dissolved iron was determined to be < 1 µg/L, and the content of zinc was 4.3 µg/L. - Executive summary:
The Study was performed according to OECD Guideline 105.
For the determination six test mixtures with two different loading concentrations (1 g/L and 10 g/L) were agitated with a magnetic stirrer for 24 hours at 20 °C. The received suspensions were filtrated through a
0.1 μm (100 nm) membrane filter. Also three blank solutions (standard water pH 8 to ISO 6341, OECD-Guidance-Document 29) were investigated. After filtration of all mixtures and blank solutions iron- and zinc-determination was performed in each filtrate with Graphite Furnace Atomic Absorption Spectrometry (GFAAS).
With a loading of 10 g zinc ferrite to water at pH 8 the dissolved iron was determined to be < 1 µg/L, and the content of zinc was 4.3 µg/L.
- Endpoint:
- transformation / dissolution of metals and inorganic metal compounds
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020-02-23 to 2021-07-22
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media
- Deviations:
- no
- Principles of method if other than guideline:
- The dissolution of Zinc Ferrite (Bayferrox 3950) in environmentally relevant test medium was assessed via ICP-OES over 28 d with a loading of 1 mg/L at target pH values of 6 and 8 and samplings after 1, 7 and 28 days.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 12.5 µg/L
- Element analysed:
- Zn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 6; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: corrected for background
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 9.16 µg/L
- Element analysed:
- Zn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 6; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: corrected for background
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- 2.38 µg/L
- Element analysed:
- Zn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 6; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: corrected for background
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 8.01 µg/L
- Element analysed:
- Zn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 8; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: corrected for background
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 3.04 µg/L
- Element analysed:
- Zn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 8; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: corrected for background
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- 1.25 µg/L
- Element analysed:
- Zn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 8; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: corrected for background
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.164 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 6; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: < LOD (0.055 µg Fe/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 2.59 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 6; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: < LOD (0.862 µg Fe/L)
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.312 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 6; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: corrected for background
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.055 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 8; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: < LOD (0.055 µg Fe/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.862 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 8; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: < LOD (0.862 µg Fe/L)
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- < 1.34 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 8; centrifugal filtration (~2.1 nm)
- Remarks on result:
- other: < LOQ (1.34 µg Fe/L)
- Details on results:
- Background concentrations:
Mean zinc background concentrations in the tests were measured to be in the range of 0.845 µg/L to 4.41 µg/L Zn. Mean iron background concentrations in the tests were in the range of 0.039 µg/L to 1.66 µg/L Fe. All results are background corrected if possible, i.e. when measured Zn or Fe background concentrations were > LOQ.
Solution pH, oxygen concentrations, temperature:
The mean temperature during the tests was always in the range of 21.5 ± 1.5 °C.
Oxygen levels of all test solutions were in the range recommended by the OECD Test Guidance 29 during the test (> 70 % of oxygen saturation at 8.5 mg/L (70 % of 8.5 mg/L = 6 mg/L). All measured values are above 6.0 ppm oxygen.
At a loading of 1 mg test item/L, the pH value of method blanks and of media containing the test item at target pH value of 6 was measured to be in the range of pH 6.0 – 6.3. The pH value of method blanks and media containing the test item at target pH value of 8 was measured to be in the range of pH 7.8 – 8.0.
Analytical measurements: Within and between vessel variations in zinc concentrations
The within / between vessel variations in vessels containing the test item are not always in accordance with the criteria defined by the guidance document (loading of 1 mg/L). At a loading of 1 mg/L, most measured Zn and Fe concentrations are close to their respective LODs/LOQs (see above). Zn and Fe are ubiquitous metals with significant background concentrations in laboratory products.
Analytical measurements - Full test:
Zinc:
- Dispersed/dissolved zinc concentrations of 0.2 µm filtered samples in the 28-d test at pH 6 (shaking at 100 rpm under dark conditions at 21.5°C) and a loading of 1 mg/L were determined with 2.91, 11.0 and 14.1 µg Zn/L after 1, 7 and 28 days, respectively.
- Dispersed/dissolved zinc concentrations of 0.2 µm filtered samples in the 28-d test at pH 8 (shaking at 100 rpm under dark conditions at 21.5°C) and a loading of 1 mg/L were determined with 1.91, 3.20 and 5.59 µg Zn/L after 1, 7 and 28 days, respectively.
Iron:
- Dispersed/dissolved iron concentrations of 0.2 µm filtered samples in the 28-d test at pH 6 (shaking at 100 rpm under dark conditions at 21.5°C) and a loading of 1 mg/L were determined with < LOQ (1.34 µg Fe /L), < LOQ (2.59 µg Fe /L) and < LOD (0.055 µg Fe /L) after 1, 7 and 28 days, respectively.
- Dispersed/dissolved iron concentrations of 0.2 µm filtered samples in the 28-d test at pH 8 (shaking at 100 rpm under dark conditions at 21.5°C) and a loading of 1 mg/L were determined with < LOQ (1.34 µg Fe /L), < LOD (0.862 µg Fe /L) and 0.321 µg Fe/L after 1, 7 and 28 days, respectively. - Conclusions:
- The transformation/dissolution test (OECD Series on Testing and Assessment Number 29, 2001) of zinc ferrite (Bayferrox 3950) at a loading of 1 mg/L at pH 6 resulted after 1, 7 and 28 days in dissolved zinc concentrations (operationally defined as the dissolved Zn fraction after centrifugal filtration (~2.1 nm)) of 2.38, 9.16 and 12.5 µg/L, respectively. At pH 8, dissolved zinc concentrations at a loading of 1 mg/L after 1, 7 and 28 days were determined with 1.25, 3.04 and 8.01 µg/L, respectively. Therefore, maximum dissolution of Bayferrox 3950 was observed with dissolved zinc concentrations of 12.5 µg/L at a pH of 6 after 28 days. Dissolved iron concentrations (operationally defined as the dissolved Fe fraction after centrifugal filtration (~2.1 nm)) at a loading of 1 mg/L after 7 and 28 days were below the limit of quantification (< 0.862 µg Fe/L, maximal LOQ) for both pH 6 and pH 8. Thus, the extent to which zinc ferrite (Bayferrox 3950) can produce soluble available ionic and other metal-bearing species in aqueous media at a loading of 1 mg/L, is limited.
Referenceopen allclose all
A similar study has been performed which is however not valid due to scattering results.
Method validation summary (ICP-MS/OES)
Zinc
Limits of detection (LODs), limits of quantification (LOQs) and correlation coefficients (r)
Limits of detection (LOD) within all measurement series: 0.135 -1.97 µg Zn/ L.
Limits of quantification (LOQ) within all measurement series: 0.406 -5.90 µg Zn/ L.
Correlation coefficients (r) within all measurement series: > 0.99921
Iron
Limits of detection (LODs), limits of quantification (LOQs) and correlation coefficients (r)
Limits of detection (LOD) within all measurement series: 0.055 -0.862 µg Fe/ L.
Limits of quantification (LOQ) within all measurement series: 0.164 -2.59 µg Fe / L.
Correlation coefficients (r) within all measurement series: > 0.9997
Zn and Fe validation data are provided in Table 2 and Table 3 as an attachment to this entry. Fe and Zn recoveries for the certified reference materials TMDA-64.3 and TMDA-52.4 were in the range of 94.7 to 113 % (see Table 2 and 3)
Description of key information
The water solubility of zinc ferrite at 20°C was determined with < 1µg/L concerning Fe according to OECD 105 (loading of 10 g/L, pH 8). In addition, the dissolution of zinc ferrite was assessed in environmental media according to the transformation/dissolution protocol (OECD Series on Testing and Assessment Number 29, 2001). At a loading of 1 mg/L, dissolved zinc concentrations (operationally defined as the dissolved Zn fraction after centrifugal filtration (~2.1 nm)) were determined with 2.38, 9.16 and 12.5 µg/L at pH 6 and with 1.25, 3.04 and 8.01 µg/L at pH 8 after 1, 7 and 28 days, respectively. Dissolved iron concentrations (operationally defined as the dissolved Fe fraction after centrifugal filtration (~2.1 nm)) at a loading of 1 mg/L after 7 and 28 days were below the limit of quantification (< 0.862 µg Fe/L, maximal LOQ) for both pH 6 and pH 8. Thus, the extent to which zinc ferrite (Bayferrox 3950) can produce soluble available ionic and other metal-bearing species in aqueous media at a loading of 1 mg/L, is limited.
Key value for chemical safety assessment
Additional information
The Study was performed according to OECD Guideline 105 at pH 8.
For the determination six test mixtures of zinc ferrite with two different loading concentrations (1 g/L and 10 g/L) were agitated with a magnetic stirrer for 24 hours at 20 °C. The received suspensions were filtrated through a
0.1 μm (100 nm) membrane filter. Also three blank solutions (standard water pH 8 to ISO 6341, OECD-Guidance-Document 29) were investigated. After filtration of all mixtures and blank solutions iron- and zinc-determination was performed in each filtrate with Graphite Furnace Atomic Absorption Spectrometry (GFAAS).
With a loading of 10 g zinc ferrite to water at pH 8 the dissolved iron was determined to be < 1 µg/L, and the content of zinc was 4.3 µg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.