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Diss Factsheets
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EC number: 234-919-5 | CAS number: 12040-43-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Nanomaterial dustiness
Administrative data
- Endpoint:
- nanomaterial dustiness
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 55992-1:2006 ("Determination of a parameter for the dust formation of pigments and extenders - Part 1: Rotation method").
- Deviations:
- yes
- Remarks:
- see below
- Principles of method if other than guideline:
- With a regular Heubach dust meter alone, it is not possible to separate inhalable, thoracic and alveolar dust fractions as defined in DIN EN 481. Therefore, the Heubach dust meter was modified in a way that a seven-stage cascade impactor was inserted instead of the filter.
This interconnection of the rotating drum and the cascade impactor requires the following special approach:
Whereas the rotating drum requires an air flow rate of approx. 20 L/min in accordance with the manufacturer’s specifications, the cascade impactor requires an air flow rate of 40 L/min in order to work properly. Therefore, 20 L/min of additional air is fed into the system via the coarse dust separator.
By intruducing a glass tubing, the dust generated in the rotating drum is now directly conveyed into the cascade impactor. The vessel used as the coarse dust seperator in the original set-up now only serves as a tool to introduce additional air and for the purpose of visual inspection. - GLP compliance:
- yes
- Type of method:
- rotating cylinder
- Remarks:
- according Heubach procedure
- Details on methods and data evaluation:
- The modified Heubach procedure was applied. In the process, the substance sample was mechanically stressed in a rotating drum (dust generation device), and both the dust already contained in this sample and the dust generated due to abrasion were removed from the dust generation device by an air current. The proportion of dust separated and considered as dust with the ability to become airborne was fed into a seven-stage cascade impactor connected to the dust generation device. Particle size classification was conducted by subsequent weighing of the respective dust masses deposited on the individual cascade stages reflecting certain particle size ranges.
The “total dustiness” value was determined as the ratio of the mass of removed dust to the total sample mass initially weighed in.
Subsequently, the dustiness values for the inhalable, thoracic and alveolar fractions according to DIN EN 481 were determined.
Test material
- Reference substance name:
- Silicic acid, aluminum magnesium sodium salt
- EC Number:
- 234-919-5
- EC Name:
- Silicic acid, aluminum magnesium sodium salt
- Cas Number:
- 12040-43-6
- Molecular formula:
- Na(0.017-1.739)Mg(0.008-0.823)Al(0.002-0.2473)SiO(2.018-3.837)
- IUPAC Name:
- aluminium(3+) magnesium(2+) sodium tris(oxosilanebis(olate))
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Data gathering
- Instruments:
- Heubach dust meter
The substance to be investigated is kept in motion in a dust generation device consisting of a rotating drum (volume: 2.2 L, 30 rpm) with integrated baffle plates. After a short period of upwards transportation the substance subsequently falls down within the drum. The airborne part of the dust is taken out of the drum by an axial air current of 20 L/min. In the process, both the airborne dust already contained in the substance and the airborne dust which has been newly generated through abrasion within the drum are collected.
Results and discussion
Dustiness index
- Key result
- Mean:
- 177.62 other: mg/g
- St. dev.:
- 2.6 other: µm
Any other information on results incl. tables
Total dustiness |
[mg/g] |
177.62 |
Inhalable fraction |
[mg/g] |
128.41 |
Thoracic fraction |
[mg/g] |
78.39 |
Respirable fraction |
[mg/g] |
26.00 |
Mass Median Aerodynamic Diameter (MMAD) |
[µm] |
13.5 |
Geometric Standard Deviation (GSD) |
[µm] |
2.6 |
Applicant's summary and conclusion
- Conclusions:
- Test item "Silic acid Aluminium Magnesium Sodium Salt" shows a (total) dustiness of 177.62 mg/g.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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