Potassium iodide

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

The test was performed according to French Standard, which was similar to OECD test guideline 202. Although there was no declaration of the GLP compliance, the study still can be considered as reliable, because it was compliant with ISO 17025, which was also accepted worldwide.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1996

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

Principles of method if other than guideline:

Norme Française AFNOR T 90 301 de janvier 1983 intitulée: « ESSAIS DES EAUX» Détermination de l'inhibition de la mobilité de Daphnia magna.

GLP compliance:

no

Remarks:

ISO 17025

Test material

Test material information

Constituent 1

Reference substance name:

iodide in KI

IUPAC Name:

iodide in KI

Constituent 2

Reference substance name:

Potassium iodide

EC Number:

231-659-4

EC Name:

Potassium iodide

Cas Number:

7681-11-0

Molecular formula:

IK

IUPAC Name:

potassium iodide

Details on test material:

no data

Sampling and analysis

Analytical monitoring:

not specified

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Daphnia magna

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

24 h

Dose descriptor:

EC50

Remarks:

In report LC50, accutually it is EC50 immobilization

Effect conc.:

10.6 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Remarks on result:

other: 3.7-16.9 mg/l

Effect concentrations 2

Duration:

48 h

Dose descriptor:

EC50

Remarks:

In report LC50, accutually it is EC50 immobilization

Effect conc.:

7.5 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Remarks on result:

other: 5.0-9.3 mg/l

Any other information on results incl. tables

Table 1 Results after 24 hours

Concentrations mg/l	Number of daphnids immobilized at 24 h					% immobilization
	A	B	C	D	Total/20
Control group	0	0	0	0	0	0
7	1	1	2	1	5	25
9	2	4	3	1	10	50
13	1	4	4	4	13	65
19	1	4	4	2	11	55
26	4	5	3	4	16	80
36	3	3	5	5	16	80
51	4	4	2	5	15	75
71	4	4	4	2	14	70
100	4	5	3	4	16	80

Table 2 Results after 48 hours

Concentrations mg/l	Number of daphnids immobilized at 48 h					% immobilization	pH	DO mg/l
	A	B	C	D	Total/20
Control group	0	0	0	0	0	0	6.9	7.4
7	1	5	2	2	8/18	44
9	5	4	3	1	13	65
13	3	4	4	4	15	75
19	5	5	5	4	19	95
26	5	5	4	5	19	95
36	5	5	5	5	20	100	6.8	7.3
51	5	5	5	5	20	100
71	5	5	5	5	20	100
100	5	5	5	5	20	100

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Remarks:

The test was performed similar to OECD test guideline 202. The validation conditions were fulfilled simultaneously, so the results for iodide can be considered as valid

Conclusions:

The 48h- EC50 immobilization of iodide to daphnia was 7.5 mg/l.

Executive summary:

The acute toxicity to daphnia of iodide was determined (Laboratoire d'Ecotoxicologie Parc technologique ALATA, 1996) according to method of “French standard”, which was similar to OECD test guideline 202. After 48 hours exposure period, the EC50 of immobilization was measured. The result of 48 hrs- EC50 was 7.5 mg/l.