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EC number: 270-185-2 | CAS number: 68412-38-4 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77899.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- transformation / dissolution of metals and inorganic metal compounds
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020-08-03 to 2021-05-25
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media
- Principles of method if other than guideline:
- The transformation/dissolution of manganese antimony titanium buff rutile (Sicotan Brown K 2711) in environmentally relevant test medium at pH 6 and 8 was determined after 1, 7 and 28 days at a loading of 1 mg/L according to the OECD Series on Testing and Assessment 29: Guidance document on transformation/dissolution of metals and metal compounds in aqueous media ENV/JM/MONO(2001)9. The transformed/dissolved amount of the test item was quantified by assessing the elemental manganese, antimony and titanium concentrations.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Ti
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Sb
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- ph 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Sb
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Sb
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Sb
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Sb
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.5 µg/L
- Element analysed:
- Sb
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOD (0.5 µg/L)
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- < 10 µg/L
- Element analysed:
- Mn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOQ (10 µg/L)
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- < 10 µg/L
- Element analysed:
- Mn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOQ (10 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 10 µg/L
- Element analysed:
- Mn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOQ (10 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 10 µg/L
- Element analysed:
- Mn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOQ (10 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 10 µg/L
- Element analysed:
- Mn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 6, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOQ (10 µg/L)
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 10 µg/L
- Element analysed:
- Mn
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- pH 8, 0.2 µm filtration
- Remarks on result:
- other: conc. of all replicates < LOQ (10 µg/L)
- Details on results:
- Ti, Sb and Mn concentrations of 0.2 µm filtered samples in the 28-d test at pH 6 and 8 at approx. 26°C were below the respective LODs (Ti, Sb: 0.5 µg/L) or LOQs (Mn: 10 µg/L) for all sampled timepoints (0h, 2h, 6h, 24h, 4d, 7d, 14d, 21d, 28d). The mean temperature during the test (26.5 °C) deviated slightly from the suggested range in the guidance document (range 20 - 25 °C ± 2 °C). This is however considered not critical and results can be regarded as conservative.
- Conclusions:
- The transformation/dissolution test (OECD Series on Testing and Assessment Number 29, 2001) of manganese antimony titanium buff rutile at a loading of 1 mg/L at pH 6 and 8 resulted after 1, 7 and 28 days in dissolved titanium, antimony and manganese concentrations (0.2 µm fractions) that were below the limit of detection (Ti, Sb: 0.5 µg/L) and/or quantification (Mn: 10 µg/L). Thus, the extent to which manganese antimony titanium buff rutile can produce soluble available ionic and other metal-bearing species in aqueous media is limited.
Reference
Test parameters and method validation:
Temperature, solution pH, oxygen concentrations:
Mean temperature as recorded by a data logger (Testo 174-T) was 26.5 ± 0.6 °C during the 28 days full test for test solutions at pH 6 and pH 8 and recovery tests.
Solution pH remained in the respective target pH range from pH 6.02 - 6.09 (target pH 6) and from pH 8.00 – 8.08 (target pH 8) during the course of the test (0h – 28d).
Oxygen levels of all test solutions were in the range recommended by the OECD Test Guidance 29 during the test (> 70 % of oxygen saturation at 8.5 mg/L (70 % of 8.5 mg/L = 6 mg/L).
Analytical measurements:
Ti, Sb and Mn concentrations of 0.2 µm filtered samples in 28-d test at pH 6 and 8 at approx. 26°C were below the respective LODs/LOQs for all sampled timepoints (0h, 2h, 6h, 24h, 4d, 7d, 14d, 21d, 28d).
Ti/Sb/Mn limit of detection (LOD): 0.5 µg/L
Ti/Sb/Mn limit of quantification (LOQ): 10 µg/L
Within- and between-vessel variations in Ti, Sb and Mn concentrations: As all data are below the respective LODs/LOQs, no assessment of elemental within- and between-vessel variations was performed.
Method validation:
All elements (Ti, Sb, Mn) were proven linear within the injected analytical range at both pH 6 and 8 (Ti, Mn, Sb: 1 - 1000 µg/L, correlation coefficients for all elements >0.99882)
Spiking experiments performed on all three elements (Ti, Sb and Mn) at pH 6 and 8 using reference material with known concentrations (10 µg/L, 100 µg/L) showed acceptable mean elemental recoveries ranging from 79.95 to 94.46 %.
Available certified reference materials:
Recovery of titanium reference material:
pH 6: 95% (certified: 25.1 ± 2.0 µg Ti /L; measured 24.0 µg/L)
pH 8: 98% (certified: 25.1 ± 2.0 µg Ti /L; measured 24.6 µg/L)
Recovery of manganese reference material:
pH 6: 100% (certified: 25.2 ± 2.0 µg Mn /L; measured 25.3 µg/L)
pH 8: 103% (certified: 25.2 ± 2.0 µg Mn /L; measured 26.1 µg/L)
Recovery of antimony reference material:
pH 6: 99% (certified: 22.7 ± 3.8 µg Sb /L; measured 22.9 µg/L)
pH 8: 104% (certified: 22.7 ± 3.8 µg Sb /L; measured 23.8 µg/L)
Description of key information
Manganese antimony titanium buff rutile (CAS:68412-38-4) does not dissolve to any relevant extent under regular environmental conditions as determined in a transformation/dissolution test (OECD Series on Testing and Assessment Number 29, 2001). Measured dissolved manganese, antimony and titanium concentrations (0.2 µm fraction) after 7 and 28 days at a loading of 1 mg/L at pH 6 and pH 8 were below the limit of detection (Ti, Sb: < 0.5 µg/L) or below the limit of quantification (Mn: < 10 µg/L). Thus, dissolution is not important for the environmental fate and behaviour of Manganese antimony titanium buff rutile in environmental compartments.
Key value for chemical safety assessment
Additional information
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