Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-537-5 | CAS number: 161075-00-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Distribution modelling
Administrative data
- Endpoint:
- distribution modelling
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Study period:
- 2015
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Model calculation using an accepted model
Data source
Referenceopen allclose all
- Reference Type:
- other: calculation based on CEMC New EQC model V.1.0
- Title:
- Environmental Fate of GALDEN LMW
- Author:
- Solvay
- Year:
- 2 015
- Bibliographic source:
- "New EQC model "Canadian Centre for Environmental Modelling and Chemistry, Trent University, Trent University, Peterborough, Ontario, Canada.
- Reference Type:
- publication
- Title:
- Assessing the Fate of New and Existing Chemicals: A Five Stage Process
- Author:
- Mackay D, Paterson, S., Kicsi, G., Di Guardo, A., Cowan, C.E.
- Year:
- 1 996
- Bibliographic source:
- Environ. Toxicol. Chem. 15 No.9 , 1618-1626
- Reference Type:
- publication
- Title:
- Evaluating the Environmental Fate of a Variety of Types of Chemicals Using the EQC Model
- Author:
- Mackay D, Paterson, S., Di Guardo, A., Cowan, C.E.
- Year:
- 1 996
- Bibliographic source:
- Environ. Toxicol. Chem. 15 No.9, 1627- 1637
- Reference Type:
- publication
- Title:
- Assessment of Chemical Fate in the Environment Using Evaluative, Regional and Local-Scale Models: Illustrative Application to Chlorobenzene and Linear Alkylbenzene Sulfonates
- Author:
- Mackay D, Paterson, S., Kicsi, G., Cowan, C.E., Di Guardo, A., Kane, D.M.
- Year:
- 1 996
- Bibliographic source:
- Environ. Toxicol. Chem. 15 No.9, 1638-1648
Materials and methods
- Model:
- calculation according to Mackay, Level I
- Calculation programme:
- CEMC New EQC model, Version 1.00 Beta - March 2011
developed by CEMC (The Canadian Centre for Environmental Modelling and Chemistry) - Release year:
- 2 011
- Media:
- air - biota - sediment(s) - soil - water
Test material
- Reference substance name:
- Hexafluoropropene, oxidized, oligomers, reduced, fluorinated
- EC Number:
- 500-537-5
- EC Name:
- Hexafluoropropene, oxidized, oligomers, reduced, fluorinated
- Cas Number:
- 161075-00-9
- Molecular formula:
- R-O(C3F6O)m-R with R= - CF3, - C2F5, -CF2H
- IUPAC Name:
- 1,1,1,2,3,3-hexafluoro-2,3-bis(1,1,2,2,2-pentafluoroethoxy)propane; 1,1,1,2,3,3-hexafluoro-2-(1,1,2,2,2-pentafluoroethoxy)-3-(trifluoromethoxy)propane; 1,1,1,2,3,3-hexafluoro-3-(1,1,2,2,2-pentafluoroethoxy)-2-(trifluoromethoxy)propane; 1,1,1,2,3,3-hexafluoro-3-{[1,1,1,2,3,3-hexafluoro-3-(trifluoromethoxy)propan-2-yl]oxy}-2-(trifluoromethoxy)propane; 1,1,1,3,3,4,6,6,7,9,9,10,12,12,12-pentadecafluoro-4,7,10-tris(trifluoromethyl)-2,5,8,11-tetraoxadodecane; 1-(difluoromethoxy)-1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,2-pentafluoroethoxy)propane; 2,2,3,5,5,6-hexafluoro-3,6-bis(trifluoromethyl)-1,4-dioxane; 2-(difluoromethoxy)-1,1,1,2,3,3-hexafluoro-3-(1,1,2,2,2-pentafluoroethoxy)propane
- Test material form:
- other: liquid
Constituent 1
Study design
- Test substance input data:
- - Molar mass: 441 g/mol (typical mean value for GALDEN HT70)
- Data temperature: 20°C
- Water solubility: 0.47 mg/L
- Vapour pressure: 14700 Pa (typical value for GALDEN HT70)
- log Pow: 5.58
- Melting point: -110°C
- Koc = 5500 (average value, calculated basing on experimental data. Ref: Chemservice 2013)
Partition coefficients (entered by the user):
Ksow (Soil-Water) = 110 (calculated)
Ksew (Sediment-Water) = 220 (calculated)
Ksus (Suspended Sediment-Water) = 1100 (calculated)
Partition coefficients (Re-elaborated by the model):
All are dimensionless on a volume basis (calculated)
Air-Water : 5659
Sediment-Water: 528
Suspended Particle-Water: 1650
Fish-Water: 19010
Soil-Water: 264
Aerosol-Air: 408
- Reaction half-life estimates for:
- Air: 3.5 10E6 hours (400 years), Ref: Young et al, 2006
- Water: 10E11 (Basing on Chemical structure negligible degradation in water is expected)
- Soil: 10E11 (Basing on Chemical structure negligible degradation in soil is expected)
- Sediment: 10E11 (Basing on Chemical structure negligible degradation in sediment is expected)
- Suspended sediment: 10E11 (Basing on Chemical structure negligible degradation in sediment is expected) - Environmental properties:
- DEFAULT PARAMETERS of the Model
Compartment Dimensions
Area (m²) Depth (m) Volume (m³)
Air 1,00E+11 1000 1E+14
Water 1,00E+10 20 2E+11
Soil 9,00E+10 0,2 1,80E+10
Sediment 1,00E+10 0,05 5,00E+08
NOTE: In Level 1 and Level 2 calculations, the air and/or water fractions of the soil and sediment compartments do not contribute to the Z value of those compartments. Only the solid components of these two compartments may contain chemical.
Phase Properties
Volume Fraction/ Density (kg/m³)
Air Compartment D: 1,20E+00
Gas Phase V: 1,00E+00 D:1,2
Aerosol (solid) V: 2,00E-11 D:2000
Water Compartment D: 1000,0025
Water (liquid) V:1,00E+00 D:1000
Suspended Sediment V:5,00E-06 D:1500
Fish V:1,00E-06 D:1000
Soil Compartment D:1500,24
Pore Air V:0,2 D:1,2
Pore Water V:0,3 D:1000
Soil Solids V:0,5 D:2400
Sediment Compartment D:1280
Sediment Solids V:0,2 D:2400
Pore Water V:0,8 D:1000
Fish Lipid Content 0,05 g/g
Suspended Sediment OC Content 0,2 g/g
Soil Solids OC Content 0,02 g/g
Sediment Solids OC Content 0,04 g/g
Advective Residence Time (hours)
Air 100
Water 1000
Soil N/A
Sediment 50000
Transport Velocities and Mass Transfer Coefficients (MTCs)
m/h m/year
Air side air-water MTC 5 4,38E+04
Water side air-water MTC 0,05 4,38E+02
Rain rate 0,0001 8,76E-01
Aerosol deposition velocity 6,00E-10 5,26E-06
Soil air phase diffusion MTC 0,02 1,75E+02
Soil water phase diffusion MTC 1,00E-05 8,76E-02
Soil air boundary layer MTC 5 4,38E+04
Sediment-water MTC 1,00E-04 8,76E-01
Sediment deposition velocity 5,00E-07 4,38E-03
Sediment resuspension velocity 2,00E-07 1,75E-03
Soil water runoff rate 5,00E-05 4,38E-01
Soil solids runoff (erosion) rate 1,00E-08 8,76E-05
Results and discussion
Percent distribution in media
- Air (%):
- 100
- Water (%):
- 0
- Soil (%):
- 0
- Sediment (%):
- 0
- Susp. sediment (%):
- 0
- Biota (%):
- 0
- Other distribution results:
- LEVEL I
The fugacity in the compartments is 5,53E-06 Pa and the corresponding activity is 3,76E-10. At saturation conditions the fugacity would be 14700 Pa, i.e. the liquid vapor pressure, and the activity would be 1.0
Any other information on results incl. tables
Level II
Assuming a constant input of 1000 kg/h and equilibrium between the air, water, soil and sediment compartments, the percentage distribution between phases is identical to that in the Level I simulation. The total amount of GALDEN LMW in the system is 99998 kg, and the residence times are as follows:
By reaction, 5,06E+06 hours or 2,11E+05 days (i.e., the overall reaction persistence).
By advection, 100 hours or 4,17 days.
In total, 100,00 hours or 4,17 days (note that the above times add reciprocally).
The fugacity in all compartments is 5,53E-06 Pa, corresponding to an activity of 3,76E-10.
Level III
In this simulation it is assumed that the chemical is emitted into the system by the modes of entry and at the rates listed below:
Into air 1000 kg/h 100 %
Into water 0 kg/h 0 %
Into soil 0 kg/h 0 %
Into sediment 0 kg/h 0 %
Into system (total) 1000 kg/h 100 %
In Level III calculations, there are four bulk compartments consisting of two or more phases. Air contains a gas phase and a solid aerosol phase; water includes liquid, suspended sediment, and fish phases; soil consists of pore air, pore water and solid phases; and sediment includes water and solid phases. The four bulk compartment fugacities are now different and reflect the mode of entry and relative reaction, advection, and intercompartmental transport rates.
COMPARTMENT |
Amount (kg) |
Amount (%) |
Concentration (g/m³) |
|||
Air (bulk) |
99998 |
kg |
100,00 |
% |
1,00E-06 |
g/m³ |
Gas Phase |
99998 |
kg |
100,00 |
% |
1,00E-06 |
g/m³ |
Aerosol (solid) |
8,16E-04 |
kg |
100,00 |
% |
4,08E-04 |
g/m³ |
Water (bulk) |
0,0266 |
kg |
2,66E-05 |
% |
1,33E-10 |
g/m³ |
Liquid Phase |
0,0259 |
kg |
2,59E-05 |
% |
1,30E-10 |
g/m³ |
Susp. Sediment |
2,14E-04 |
kg |
2,14E-07 |
% |
2,14E-07 |
g/m³ |
Fish (wet wgt.) |
4,93E-04 |
kg |
4,93E-07 |
% |
2,46E-06 |
g/m³ |
Soil (bulk) |
4,02 |
kg |
4,02E-03 |
% |
2,23E-07 |
g/m³ |
Pore Air |
3,60 |
kg |
3,60E-03 |
% |
1,00E-06 |
g/m³ |
Pore Water |
9,54E-04 |
kg |
9,54E-07 |
% |
1,77E-10 |
g/m³ |
Solids |
0,420 |
kg |
4,20-04 |
% |
4,66E-08 |
g/m³ |
Sediment (bulk) |
0,0204 |
kg |
2,04E-05 |
% |
4,09E-08 |
g/m³ |
Pore Water |
1,54E-04 |
kg |
1,54E-07 |
% |
3,84E-10 |
g/m³ |
Solids |
0,0203 |
kg |
2,03E-05 |
% |
2,03E-07 |
g/m³ |
The total mass of GALDEN LMW in the system is 1,00E+05 kg
The overall residence time is 100 hours or 4,17 days.
The reaction residence time is 5,06E+06 hours or 2,11E+05 days.
The advection residence time is 100 hours or 4,17 days.
The intercompartmental transport rates are as follows:
Air to water 9,10E-05 kg/h
Air to soil 1,79 kg/h
Water to air 6,48E-05 kg/h
Water to sediment 1,20E-06 kg/h
Soil to air 1,79 kg/h
Soil to water 8,37E-07 kg/h
Sediment to water 7,90E-07 kg/h
Applicant's summary and conclusion
- Conclusions:
- According to the model results, when emitted to the environment practically 100% of the substance is expected to distribute in the atmospheric compartment at every degree of complexity (Level I, II and III).
Distribution in water, soil, sediment are expected to be negligible. - Executive summary:
The environmental distribution of GALDEN LMW has been evaluated by the tool developed by the Canadian Centrefor Environmental Modelling and Chemistry, Trent University, Peterborough, Ontario (Canada), the New EQC (Equilibrium Criterion) model V.1.0 (2011).
According to the Mackay distribution model, three degrees of complexity are treated in this tool, Levels I and II assume thermodynamic equilibrium is achieved; Level II includes advective and reaction processes. Level III is a non-equilibrium, steady-state assessment of chemical fate in the environment.
The model is applicable to three types of chemicals: chemicals that partition into all media (Type 1), involatile chemicals (Type 2), and chemicals with zero or near-zero solubility (Type 3). GALDEN LMW is treated as Type 1 chemical.
For LEVEL I and LEVEL II predictions the default values of the model have been kept:
1) Total Mass of the chemical in the environment= 100000 kg
2) Emission rate = 1000 kg/h
For LEVEL III prediction, since basing on the substance properties only emissions to the atmosphere are expected, the following emission rates have been set:
- to air: 1000 kg/h
- to water: 0 kg/h
- to soil: 0 kg/h
- to sediment: 0 kg/h
According to the model results, when emitted to the environment practically 100% of the substance is expected to distribute in the atmospheric compartment at every degree of complexity (Level I, II and III).
Distribution in water, soil, sediment is expected to be negligible.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.