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EC number: 293-215-6 | CAS number: 91052-54-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility (WS < 0.15 mg/L)
Key value for chemical safety assessment
Additional information
No experimental data evaluating the acute toxicity of Glycerides, C16-18 mono-, di- and tri- (CAS No. 91052-54-9) to fish species are available. Therefore, data from a structurally related analogue substance, Glycerides, C14-18 mono- and di- (CAS No. 67701-33-1) are used as read-across in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Both substances are esters formed from the combination of mainly C16 and C18 fatty acids and glycerol. The behaviour of these substances in the water phase is expected to be very similar based on low water solubility values < 1 mg/L and log Kow values > 4. Based on this information, reading-across from Glycerides, C14-18 mono- and di- to Glycerides, C16-18 mono-, di- and tri- is justified.
Two studies evaluating the acute toxicity of Glycerides, C14-18 mono- and di- (CAS No. 67701-33-1) are available. The key study (Guhl, 1992) was conducted according to ISO 7346-1, under GLP conditions. Danio rerio were exposed to two concentrations of test substance (3000 and 10000 mg/L) for 96 hours within a semi-static water regime. After the exposure period, no mortality was observed in any of the treatment groups, or in the control. Therefore, the LC50 (96 h) was determined to be > 10,000 mg/L (nominal concentration). The supporting study (Richterich and Mühlberg, 2001) was performed following ISO 7346-1 as well. Danio reriowas exposed to 100, 1000 and 10000 mg test substance/L within a semi-static water regime. After 96 hours, only one fish died at a concentration of 1000 mg/L and therefore, the LC50 (96 h) was determined to be > 10,000 mg/L.
Based on the results obtained for the structurally related analogue substance (in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5), no acute toxicity ofGlycerides, C16-18 mono-, di- and tri- to fish species up to the limit of its water solubility (< 0.15 mg/L) is expected.
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