Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 203-157-5 | CAS number: 103-90-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
General information:
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
• After inhalation: Supply fresh air; consult doctor in case of complaints.
• After skin contact:
Wash skin with soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention, if needed. Thoroughly clean and dry contaminated clothing and shoes before reuse.
• After eye contact: Rinse opened eye for several minutes under running water.
• After swallowing: Call for a doctor immediately.
• Information for doctor:
• The following symptoms may occur:
Respiratory paralysis, gastric pain, drowsiness, dizziness, unconsciousness, agitation, nausea,vomiting, coma.
Fire-fighting measures
• Suitable extinguishing agents: Water spray, dry chemical, alcohol resistant foam.
• Special hazards caused by the substance, its products of combustion or resulting gases:
Combustible material. Risk of dust explosion. Development of hazardous combustion gases or vapours possible in the event of fire. Fire may cause evolution of Nitrogen oxides, Nitrous gases
• Protective equipment:
Firefighters should be equipped with self-contained breathing apparatus and turn-out gear.
• Additional information
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Accidental release measures
• Person-related safety precautions:
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Avoid breathing vapors, mist or
gas.
Ensure adequate ventilation. Evacuate personnel to safe areas. Remove all sources of ignition.
• Measures for environmental protection:
Do not allow to enter sewers/ surface or ground water.
Prevent further leakage or spillage if safe to do so. Discharge into the environment must be avoided.
• Measures for cleaning/collecting:
Pick up and arrange disposal without creating dust. Sweep up and shovel. Reduce airborne dust and prevent
scattering by moistening with water. Keep in suitable, closed containers for disposal. Use non-sparking tools and equipment.
Handling and storage
• Handling:
• Information for safe handling:
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation
at places where dust is formed. Normal measures for preventive fire protection.
• Information about fire - and explosion protection: Keep away from sources of ignition.
• Storage:
• Requirements to be met by storerooms and receptacles: Protect from light.
• Information about storage in one common storage facility: Store away from incompatibles.
• Further information about storage conditions:
Preparations containing this substance should be stored at a temperature less than 40 deg C, preferably
between 15-30 deg C; freezing of the oral solution or suspension should be avoided. Store in a tightly closed container. Avoid contact with air or light.
Containers of this material may be hazardous when empty since they retain product residues (dust, solids)
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
• Additional information about design of technical facilities:
Provide an emergency eye wash fountain and quick drench shower in the immediate work area.
• Ingredients with limit values that require monitoring at the workplace: Not required.
• Personal protective equipment:
• General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Wash hands before breaks and at the end of work.
Handle in accordance with good industrial hygiene and safety practice.
Respiratory protection:
(Contd. of page 3)
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level
protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
• Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Stability and reactivity
• Thermal decomposition / conditions to be avoided:
No decomposition if used according to specifications.
Sensitive to light. Avoid strong heating.
• Materials to be avoided: Oxidizing agents, bases, acids.
• Dangerous decomposition products:
In the presence of heat and water, substance will hydrolyze into acetic acid and p-aminophenol.
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides (NOx)
• Additional information: Risk of dust explosion.
Disposal considerations
• Recommendation
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.
• European waste catalogue
07 05 : Wastes from the MFSU(Manufacture, Formulation, Supply and Use) of pharmaceuticals.
• Uncleaned packaging:
• Recommendation:
Disposal must be made according to official regulations.
Dispose off as unused product.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.