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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

LD50 oral (rat, combined): 2900 mg/kg bw  (equivalent to 3.5 ml/kg bw)
LD50 dermal (rabbit, combined): >2000 mg/kg bw
LC50 inhalation (rat, combined): >15 - < 376 mg/L

Key value for chemical safety assessment

Additional information

In an acute oral toxicity study in the rat a combined LD50 value of 3.5 ml/kg bw, equivalent to 2900 mg/kg bw, was derived (80 -0080-DKT). In another acute oral toxicity study in the rat performed in 1976, a combined LD50 value of 2425 mg/kg bw was derived (TSCA Section 8(e), Doc-ID 878214248).

In an acute dermal toxicity study in the rabbit a combined LD50 value of >2000 mg/kg bw was derived (TSCA Section 8(e), Doc-ID 878214250).

In an acute inhalation toxicity study in the rat an LC50 value of >15 - < 376 mg/L (vapour) was derived (TSCA Section 8(e), Doc-ID 878214252).

Justification for classification or non-classification