Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 416-740-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- not applicable
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The reliability rating was 2 because the data are calculated
- Qualifier:
- according to guideline
- Guideline:
- other: Computer Model
- Principles of method if other than guideline:
- Formerly called BCFWIN™, this program estimates fish bioconcentration factor and its logarithm using two different methods. The first is the traditional regression based on log KOW plus any applicable correction factors, and is analogous to the WSKOWWIN™ method. The second is the Arnot-Gobas method, which calculates BCF from mechanistic first principles. BCFBAF also incorporates prediction of apparent metabolism half-life in fish, and estimates BCF and BAF for three trophic levels.
- GLP compliance:
- no
- Radiolabelling:
- no
- Type:
- BCF
- Value:
- 0.895
- Basis:
- other: Calculated
- Time of plateau:
- 0 d
- Calculation basis:
- other: EPiSuite 4.0 BCFBAF v3.00
- Remarks on result:
- other: BCF (Arnot-Gobas method)
- Remarks:
- Conc.in environment / dose:NA
- Type:
- BAF
- Value:
- 2.236
- Basis:
- other: Calculated
- Time of plateau:
- 0 d
- Calculation basis:
- other: EPI Suite 4.0 BCFBAF v 3.0
- Remarks on result:
- other: BAF (Arnot-Gobas method)
- Remarks:
- Conc.in environment / dose:NA
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test substance has a low potential to bioconcentrate, based on the estimated BCF value of 0.8953 and BAF value of 2.236 from EPI Suite v4.0. This indicates that the substance is not likely to be bioaccumulative.
- Executive summary:
The test substance has a low potential to bioconcentrate, based on the estimated BCF value of 0.8953 and BAF value of 2.236. In addition, the substance has a calculated Log Kow of 13.3. As pointed out in the REACH guidance document, Chapter R11.1.3.2 (bioaccumulation assessment, pg 28), “the aquatic BCF of a substance is probably lower than 2000 L/kg if the calculated Log Kow is higher than 10” (ECHA 2008). Collectively, these calculations support the conclusion that test substance is not expected to be bioaccumulative.
Reference
Time of plateau was not applicable to calculated BCF or BAF values. Value of 0 day was entered so as to fill in field since there was no choice to enter none or not applicable.
Description of key information
The test substance has a low potential to bioconcentrate, based on the estimated BCF value of 0.8953 and BAF value of 2.236 from EPI Suite v4.0. This indicates that the substance is not likely to be bioaccumulative.
In addition, the substance has a calculated Log Kow of 13.3. As pointed out in the REACH guidance document, Chapter R11.1.3.2 (bioaccumulation assessment, pg 28), “the aquatic BCF of a substance is probably lower than 2000 L/kg if the calculated Log Kow is higher than 10” (ECHA 2008). Collectively, these calculations support the conclusion that test substance is not expected to be bioaccumulative.
Key value for chemical safety assessment
- BCF (aquatic species):
- 0.895 dimensionless
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.