Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-693-8 | CAS number: 1268005-68-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96h LC50 (Oncorhynchus mykiss) = 3.6 mg/L (nominal concentration, OECD 203)
96h LC50 (Cyprinodon variegates) = 4.1 mg/L (measured concentration, marine water, ASTM E-35 1980)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 3.6 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 4.1 mg/L
Additional information
Since no reliable chronic fish test is available for C12-14AS K (CAS 1268005-68-0), in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5, a read-across to another structurally related category members was conducted. Read-across data from the following substances were used: two C12-14 mixtures: C12-14AS TEA (CAS 90583-18-9) and C12-14AS Na (CAS 85586-07-8) and two pure homologues: C12AS Na (CAS 151-21-3) and C14AS Na (CAS 1191-50-0). Toxicity of alkyl sulfates is dependent of the carbon chain length and the influence of the counter ion can be neglected.
Two short-term fish toxicity studies are available for C12-14AS TEA (CAS 90583-18-9). The key, GLP-compliant test was performed in semi-static conditions with rainbow trout (Oncorhynchus mykiss) according to OECD 203 (Wetton 1996). Mortality of fish caused by the test substance was determined after 24, 48, 72 and 96 hours of exposure to the concentrations up to 18 mg/L of 40% pure technical product (in water) corresponding to 7.2 mg a.i./L. No analytical measurements of test concentrations are available. The results showed that the 96-hour LC50 value was 3.6 mg a.i./L (nominal concentration). Composition of carbon chains of the tested category member C12-14AS TEA (CAS 90583-18-9) is the same as of C12-14AS K (CAS 1268005-68-0): both contain on average 58.1% of C12 and 32.6% of C14 chains. Due to structural and property similarity with the tested category member, this value is considered as a reliable LC50 value for C12-14AS K (CAS 1268005-68-0).
The other non-GLP study available for C12-14AS TEA (CAS 90583-18-9) was performed with golden orfe (Leuciscus idus) in static conditions according to DIN 38412 - L15 method (Richterich 2001). Mortality of fish was determined after 24 and 48 hours of exposure to the concentration up to 150 mg/L solution of 42% test substance in water, equivalent to 63 mg a.i./L. Analytical check of test concentrations is not available. The 48-hour LC50 was determined to be 9.2 mg a.i./L (nominal concentration).
Two GLP studies (Wetton, KAO, 1996; Wetton, Elementis, 1996) were conducted with C12-14AS Na (CAS 85586-07-8) according to OECD 203 under semi-static conditions on rainbow trouts (Oncorhynchus mykiss). In the first study the fish were exposed to the test concentrations up to 10 mg/L (nominal) for 96 hours. Analytical monitoring was not performed. The reported LC50-value was 3.6 mg/L (nominal concentration). In the other test the nominal concentrations reached 18 mg/L of 30% pure product (in water). The reported 96-hour LC50 was 11 mg/L equal to 3.3 mg a.i./L.
Toxic effects of CAS 151-21-3 to fathead minnow (Pimephales promelas) were studied in a non-GLP test performed according to OECD 203 guideline (Rawlings 2004). Fish were exposed in a flow-through system to five test concentrations up to 48 mg/L of nominal concentration, corresponding to 40 mg/L of measured concentration. Mortality of fish was evaluated every 24 hours. The test substance was determined to have the 96-hour LC50 value of 29 mg/L (measured concentration). Moreover, the short term effects of CAS 151-21-3 were studied on the marine sheepshead minnow Cyprinodon variegatus (Roberts et al. 1982). This non-GLP test was performed according to ASTM E-35 (1980) method. Fish were exposed to five test concentrations in brackish water (salinity 10 ‰) under static conditions. The 96h LC50 value of 4.1 mg/L was determined (measured concentration).
One non-GLP short-term test with golden orfes (Leuciscus idus) preformed according to DIN 38412 - L15 guideline is available for C14AS Na (CAS 1191-50-0; Richterich 2001). Fish were exposed in a static test for 48 hours to the nominal concentrations up to 8 mg/L of 25.7% pure test substance (in water). Analytical measurements are not available. Mortality of fish was evaluated after 6, 24 and 48 hours of exposure. The 48-hour LC50 value was determined to be 3.2 mg a.i./L (nominal concentration).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.