Registration Dossier
Registration Dossier
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EC number: 202-448-4 | CAS number: 95-76-1
Biotransformation and kinetics
Administrative data
- Endpoint:
- biotransformation and kinetics
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable publication
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Reductive dehalogenation of dichloroanilines by anaerobic microorganisms in fresh and dichlorophenol acclimated pond sediment.
- Author:
- Struijs, Rogers
- Year:
- 1 989
- Bibliographic source:
- Appl. Environ. Microbiol. 55,|2527-2531
- Reference Type:
- review article or handbook
- Title:
- 2,4-Dichloranilin; 2,5-Dichloranilin; 3,4-Dichloranilin
- Author:
- Beratergremium für umweltrelevante Altstoffe (BUA)
- Year:
- 1 994
- Bibliographic source:
- Wissenschaftliche Verlagsgesellschaft, BUA report 140
- Reference Type:
- secondary source
- Title:
- 3,4-dichloroaniline (3,4-DCA)
- Author:
- EU-Risk Assessment Report
- Year:
- 2 006
- Bibliographic source:
- EUR 22235 EN; ISSN 1018-5593
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Type of medium:
- other: Seesediment, adaptiert
Test material
- Reference substance name:
- 3,4-dichloroaniline
- EC Number:
- 202-448-4
- EC Name:
- 3,4-dichloroaniline
- Cas Number:
- 95-76-1
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 3,4-dichloroaniline
Constituent 1
Results and discussion
Identity of transformation productsopen allclose all
- No.:
- #1
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- 3-chloroaniline
- Inventory number:
- InventoryMultipleMappingImpl [inventoryEntryValue=EC 203-581-0]
- CAS number:
- 108-42-9
- No.:
- #2
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- 4-chloroaniline
- Inventory number:
- InventoryMultipleMappingImpl [inventoryEntryValue=EC 203-401-0]
- CAS number:
- 106-47-8
Any other information on results incl. tables
Sediment
Biodegradation tests under anaerobic conditions with fresh-water-sediment and pond-sediment
indicate primary degradation through reductive dechlorination to monochloroaniline (3- and
4-chloroaniline) only. The dechlorination started after 20 days of incubation in unacclimated
sediments. Approximately 90% of the 3,4-DCA was dechlorinated within the next 40 days. After
60 days 44% of the 3,4-DCA was present as 3-chloroaniline and 33% as 4-chloroaniline. Further
degradation of the monochloroanilines was not observed in these studies. The
monochloroanilines, however, appeared to be resistant to further dechlorination (Struijs and
Rogers, 1989). No information on mineralisation is available.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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