Registration Dossier
Registration Dossier
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EC number: 404-360-3 | CAS number: 119313-12-1 CG 25-369; IRGACURE 369; TK 11-319
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1989
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: - EEC Directive 84/449, A.7
- GLP compliance:
- no
- Medium:
- standard fat
- Remarks:
- HB 307, batch 24/11
- Solubility:
- 3.24 other: g/100g of fat
- Temp.:
- 37 °C
- Remarks on result:
- other: Standard deviation: 0.16g/100g fat
- Test substance stable:
- yes
- Conclusions:
- Fat solubility of test substance was determined to be 3.24 g/100 g of fat at 37°C
- Executive summary:
In this guideline (EU A. 7) study, the fat solubility of the test material (EC 404-360-3) was determined to be 3.24 g/100 g of fat at 37°C
Reference
Individual results:
| Stirring period at 37 °C (h) | Fat solubility in g/100 g of fat 1 hour preequilibration at |
|
| 30 °C | 50 °C | |
| 5 | 3.38 / 3.32 | 3.46 / 3.46 |
| 24 | 3.10 / 3.03 | 3.17 / 3.17 |
| 48 | 3.10 | 3.17 |
There are no significant differences among the results of preequilibration at 30 °C and 50 °C. The solubility at 37 °C can be taken as the mean value of the ten individual results.
Description of key information
Study conducted to recognised testing guidelines
Key value for chemical safety assessment
- Solubility in mg/100g standard fat:
- 3 240
- At the temperature of:
- 37 °C
Additional information
3240 mg/100g of fat at 37°C
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