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EC number: 208-797-9 | CAS number: 542-05-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Appearance/physical state/colour
Experimental results indicate the chemical 3-oxoglutaric acid to be a colouless amorphous organic solid with characteristic odour at 30oC and 990 hPa
Melting point/freezing point
The melting point of 3-oxoglutaric acid was determined to be 138oC at atmospheric pressure of 990 hPa. The sample did not decompose or submlimate at the melting point. This value at 101 325 Pa is equivalent to 141.24oC
Boiling point
The experimental value of the boiling point of the chemical 3-oxoglutaric acid was found to be 300oC at atmospheric pressure of 990 hPa. There was no decomposition observed at the boiling point. This value at 101 325 Pa is equivalent to 307.04oC
Density
The density of 3-oxoglutaric acid by the mass by volume method was found to be 0.60 g/cm3 at room temperature of 30 degC. This value at 20oC is equivalent to 0.90 g/cm3
Particle size distribution (Granulometry)
The particle size distribution (granulometry) of 3-oxoglutaric acid by the sieve analysis method was found to be in the range of 75 micrometer to 300 micrometer. Majority of the particles were found to be in the size range of 150 micrometer.
Vapour pressure
Vapour pressure of 3-oxoglutaric acid was estimated to be 0.0000409 mm Hg (Modified Grain Method). This value when converted into pascal is equivalent to 0.00545 Pa.
Partition coefficient
The experimental partition co-efficient value of 3-oxoglutaric acid was found to be 0.3157 (Log Pow = -0.500) at a temperature of 30oC and pH of 2.60
Water solubility
The water solubility of 3-oxoglutaric acid was found to be 510 g/L at 30oC and neutral pH. Thus, it is concluded that the chemical is very soluble in water.
Solubility in organic solvents / fat solubility
The solubility of 3-oxoglutaric acid in methanol was found to be 465.1 g/L at 30oC. Thus, it is concluded that the chemical is very soluble in methanol.
The solubility of 3-oxoglutaric acid in petroleum ether was found to be 332 mg/L at 30oC. Thus, it is concluded that the chemical is moderately soluble in petroleum ether.
Surface tension
In accordance with column 2 of Annex VII, since surface activity is not a desired property of the chemical, this end point was considered for waiver
Flash point
The experimental value of flash point of 3-oxoglutaric acid by the open cup method was found to be 200 degC at 990hPa.Thus, it is inferred that the chemical shall not have a tendency to flash. This value at 101 325 Pa is equivalent to 204.69oC
Auto flammability
3-oxoglutaric acid does not catch fire at room temperature and pressure. Thereby, it can be inferred that the chemical is not auto-flammable.
Flammability
The chemical 3-oxoglutaric acid caught fire when the flame of bunsen burner having temperature of 950oC was brought in contact with it. However, since such high temperature conditions do not exist during transportation or use of the chemical it can be concluded that the chemical is non-flammable.
Explosiveness
This end point was considered for waiver since there are no chemical groups associated with explosive properties present in the molecule of 3-oxoglutaric acid.
Oxidising properties
The chemical 3-oxoglutaric acid was found to have mild oxidising property since 122.71 ml of KMnO4 was required to get the end point of the redox titration. However, this oxidising property is very mild and does not classify the chemical as an oxidising solid.
pH
The pH of 1% solution of 3-oxoglutaric acid was found to be 2.10 at 25oC. Thus, it can be concluded that the chemical is strongly acidic.
Dissociation constant
The experimental average value of the dissociation constant of 3-oxoglutaric acid was found to be 0.00009411 at 30oC. This value is equivalent to 0.0001411 at 20oC considering the dissociation reaction to be an endothermic reaction.
Viscosity
The chemical 3-oxoglutaric acid is a solid and since viscosity is an inherent property of liquids, this end point was considered for waiver
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