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EC number: 940-411-0 | CAS number: 1353749-74-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study was selected as the key study because the information provided for the hazard endpoint is sufficient for the purpose of classification and labelling and/or risk assessment.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling point/boiling range)
- Deviations:
- no
- Remarks:
- The study was conducted according to the test guidelines in effect at the time of study conduct.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Deviations:
- no
- Remarks:
- The study was conducted according to the test guidelines in effect at the time of study conduct.
- GLP compliance:
- yes
- Type of method:
- method according to Siwoloboff
Test material
- Reference substance name:
- 2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylidene]propanehydrazide hydrochloride
- EC Number:
- 940-411-0
- Cas Number:
- 1353749-74-2
- Molecular formula:
- C10H14ClN3O5
- IUPAC Name:
- 2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylidene]propanehydrazide hydrochloride
- Details on test material:
- - Purity: 99.97%
Constituent 1
Results and discussion
Boiling point
- Decomposition:
- yes
- Decomp. temp.:
- >= 220 - <= 221 °C
- Remarks on result:
- other: The test substance melted/foamed between 220 and 221°C, leaving a black powdery residue. No boiling point/range was observed.
Any other information on results incl. tables
Typically, when a test material melts, a boiling point capillary is inserted below the liquid depth of the melted test substance. At no point during the testing was this possible with this compound. As the temperature increased, the solid test substance began to undergo significant colour changes. The original white to off-white colour of the test material changed as a function of temperature. The test substance became darker in colour with increasing temperature. At 220.5°C, a phase change appeared to take place. The test substance appeared to melt and foam. The now black test substance rose up the sides of the boiling point tube. The original depth of the test material inside each sample tube was approximately 8 mm. After the testing, the black, solid powdery residue height inside each tube was approximately 23 mm. Even if a boiling point capillary could have been inserted inside the boiling point tube (during this phase transition), the sample colour would have prevented any observance of sample bubbling. At a temperature of 250°C, the testing for each sample was discontinued. These colour changes are an indication of thermal degradation. The test substance did not provide a boiling point/range for any of the three tests.
Applicant's summary and conclusion
- Conclusions:
- This study and the conclusions which are drawn from it fulfil the quality criteria (validity, reliability, repeatability).
The test substance thermally degraded as the instrument block temperature approached 220°C. No boiling point/range was observed. - Executive summary:
The boiling point was determined using a modification of the Siwoloboff procedure described in OECD 103. Subsamples of the test substance were heated (in boiling point tubes and capillaries) using a temperature-controlled metal heating block instead of a liquid bath.
As the test substance was heated it appeared to melt and foam, then become a black, solid, powdery residue. The test substance thermally degraded as the instrument block temperature approached 220°C. No boiling point/range was observed.
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