Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 481-730-0 | CAS number: 848301-65-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The UVCB substance 'Naphtha (Fischer-Tropsch), light, C4-10 - branched and linear' had an experimentally determined log KOW of 4.4 to > 6.5 (whereas 60.2% of the test material had a log KOW-value greater than 6.50) and would therefore be expected to have the potential to bioaccumulate. However, the bioaccumulation potential may not be realised in vivo because of the high degradability potential of the component hydrocarbons. In this context a recent review can be taken into account, which demonstrates / underpins this thesis (Rojo, 2009; see IUCLID section 5.6 for more details).
Moreover, a systematic review of the persistence and bioaccumulation properties of petroleum hydrocarbons is available (whereas measured data and model predictions were used to develop an evidence-based conclusion), which supports the conclusion that none of the branched and linear constituents that comprise 'Naphtha (Fischer-Tropsch), light, C4-10 - branched and linear' meet the PB criteria. Accordingly, none of the constituents that comprise 'Naphtha (Fischer-Tropsch), light, C4-10 - branched and linear' has a bioconcentration factor in aquatic species higher than 2000.
Some further information is available regarding bioaccumulation, from a solid phase micro extraction (SPME) study (see EPSR Harris, 2013). SPME is a biomimetic extraction system that tries to mimic the way organisms extract chemicals from water. A biomimetic extraction technique using SPME in conjunction with gas chromatography (GC) was employed to assess the level of water soluble hydrocarbons and hence the potential toxicity of water accommodated fractions (WAFs) for a range of GTL products. In addition, the toxicity of WAFs was also monitored using an in-vitro MicrotoxTMassay, a biosensor-based measurement system based on Vibro Fischeri bacteria. In this study the majority of GTL samples (including the registration substance GTL Naphtha) analysed using SPME-GC indicated a low total peak area for soluble hydrocarbons (on average less than 12 000) and hence toxicity, with no detectable toxicity using the MicrotoxTM assay. The low total peak area for soluble hydrocarbons for these substances is indicative of a low potential to bioaccumulate. The related C8 -16 ("GTL Kerosine") and C4 -10 ("GTL Naphtha") samples, consisting of shorter chain hydrocarbons, produced a more soluble hydrocarbon fraction, and GTL Naphtha resulted in a moderate level of toxicity detected with the MicrotoxTM assay. The level of toxicity seen with the GTL Naphtha is, however, considerably less than that seen with the crude oil gasoline.
Aquatic bioconcentration factors (BCF) for consituents of GTL Naphtha were calculated using a validated QSAR method. Further details are given in the attached QM(P)RF documents.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.