Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-173-0 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion)
Test material
- Reference substance name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- Cas Number:
- 208711-51-7
- Molecular formula:
- C9H9NO2
- IUPAC Name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- Reference substance name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- IUPAC Name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
Constituent 1
Constituent 2
Test animals
- Species:
- rabbit
- Strain:
- Himalayan
Test system
- Type of coverage:
- semiocclusive
- Duration of treatment / exposure:
- 4 hours
- Observation period:
- 14 days
- Number of animals:
- 3
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- other: Erythema/Eschar
- Basis:
- mean
- Time point:
- other: 72 h
- Score:
- 1
- Max. score:
- 2
- Remarks on result:
- other: Due to the red colour of the TS observation of erythema was not possible 72 hours after patch removal. No signs of systemic intolerances. Changes not fully reversible within an observation period of 14 days.
- Irritation parameter:
- edema score
- Basis:
- mean
- Time point:
- other: 72 hours
- Score:
- 0
- Max. score:
- 0
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
