Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: extracted from ECHA database
Title:
Unnamed
Year:
1991

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
EC Number:
406-030-4
EC Name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
Cas Number:
105812-81-5
Molecular formula:
C13H18FNO
IUPAC Name:
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine

Test solutions

Vehicle:
yes
Details on test solutions:
the substance was directly dispersed in water.

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
not specified
Water media type:
not specified
Total exposure duration:
48 h

Test conditions

Hardness:
50 mg CaCO3/l

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
15 mg/L
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
5.8 mg/L
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
5.8 mg/L
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
1 mg/L

Applicant's summary and conclusion

Conclusions:
the substance is classified as toxic to aquatic organisms.