Registration Dossier
Registration Dossier
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EC number: 485-140-4 | CAS number: 515815-48-2
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 4 May - 18 May 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted in GLP compliance and in accordance with several internationally established guidelines (OECD, EEC, EPA guidelines, see below).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- pycnometer method
Test material
- Reference substance name:
- -
- EC Number:
- 485-140-4
- EC Name:
- -
- Cas Number:
- 515815-48-2
- Molecular formula:
- C33 H30 N4 O2 x HCl
- IUPAC Name:
- 4’-(2-Propyl-4-methyl-6-(1-methylbenzimidazolyl-2-yl)-benzimidazol-1-ylmethyl)biphenyl-2-carbonsäure Hydrochlorid
- Details on test material:
- - Name of test material (as cited in study report): BIBR 277 CL
- Molecular formula (if other than submission substance): C33H30N4O2*HCl
- Molecular weight (if other than submission substance): 514.6 + 36.5 g/mol
- Structural formula attached as image file (if other than submission substance): see reference substance
- Physical state: solid; sligh grey
- Analytical purity: 99.8 %
- Purity test date: 17. october 2005
- Lot/batch No.: 9
- Expiration date of the lot/batch: april 2006
- Storage condition of test material: at room temperature, dark and dry
Constituent 1
Results and discussion
Density
- Type:
- relative density
- Density:
- 1.286
- Temp.:
- 20 °C
Any other information on results incl. tables
| Mass (g) | Volume (cm3) | Density (g/cm3) | |
| Sample 1 | 0.858 | 0.668 | 1.284 |
| Sample 2 | 0.887 | 0.690 | 1.286 |
| Sample 3 | 0.870 | 0.675 | 1.289 |
| Sample 4 | 1.233 | 0.958 | 1.287 |
| Sample 5 | 1.073 | 0.835 | 1.285 |
| Average density (g/cm3) | 1.286 | ||
| Relative density | 1.286 | ||
| standard deviation | 0.002 | ||
| (95%) Confidence Interval | 0.0024 | ||
Applicant's summary and conclusion
- Conclusions:
- A relative density of 1.286 at 20°C was determined in a reliable study conducted according to an appropriate OECD test method.
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