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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

Overall conclusion:

Based on the assessment described in the subsections above the submission substance is not a PBT / vPvB substance.

Justification:

Persistence:

Sodium isopentyl xanthate (CAS#2540-36-5) is readily biodegradable

Simulating test water, sediment(Analytical Department of Institute of Heavy Organic Synthesis "BLACHOWNIA", 2012, Kędzierzyn-Koźle, Poland; GLP certificate no. 4/2010/DPL).KS;Reliability 1; robust study summary available; Data owner – MINOVA-KSANTE Sp. z o. o.

Method: Dissolved Organic Carbon (DOC) Die-Away, (Regulation EC No 440/2008, method C.4-A)

A measured volume of inoculated mineral medium containing a known cocentration of the test substance (10-40 mg/l) as a source of organic carbon is aerated in the dark or diffused light at 22 +/- 20C. Degradation is followed by DOC analysis at frequent intervals over 28-day period.

After 21 days biodegradation of sodium isopentyl xanthate: D21days= 83.1+/_1.4%

The above results indicate that sodium isopentyl xanthate (CAS# 2540-36-5) is ready biodegradable

- pass level, according to OECD 301:

-pass value in the 10 day window (form 0 day to 10 day)is 70% removal of DOC,

 

Bioaccumulation:

Partition coefficient n-octanol/water.

Experimental result.Shake flask method according to A.8, EC No.440/2008 and OECD 107 (Lewandowska M., Bombińska D., Institute of Industrial Organic Chemistry, Active Ingredients Synthesis and Technology Department, Report no BS-08/14, March 2014, GLP Compliance No 8/2011/DPL).

Calculated values of sodium isopentyl xanthate (CAS#2540-36-5) partition coefficient 1-octanol/water, supporting study: logPow =-1.08± 0.09

 

Vial number

 1

2

 3

4

 5

6

      

 

Volume 1-octanol phase/volume of water phase

1:1

1:2

2:1

Pow= C1-octanol/Cwater

0.0720

0.0715

0.1119

0.0993

0.00694

0.0908

log Pow= log(C1-octanol/Cwater)

-1.14

-1.15

-0.95

-1.00

-1.16

-1.10

Average

log Pow+ standard deviation

-1.15± 0.01

-0.98± 0.04

-1.10± 0.08

Average log

log Pow-1.08± 0.09

 

Estimated at 250C Partition coefficient n-octanol/water of sodium isopentyl xanthate (CAS# 2540 -36 -5):

log Kow= -1.08 (Method: shake flask - Lewandowska M., Bombińska D. )

Partition coefficient n-octanol/water of sodium isopentyl xanthate (CAS# 2540-36-5) is very low.

BCFWIN - Arnold-Gobas BCF&BAF methods (including biotransformation rate estimates for fish) (US EPA. 2011. Estimation Program Interface Suite for Microsoft Windows v 4.10 United States Environment Protection Agency, Washington, DC, USA, http: //epa. gov/oppt/exposure/pubs/episuite. htm)

 (file: //C: \(x86) Common Files\QSAR Toolbox\Ver2.2\config)

BAF =14.45dm3/kg wet-upper trophic for potassium pentyl xanthte

 

PBT Profiler Estimate (http: //www. pbtprofiler. net/ChemDetails?I=0)

The estimated bio-concentration factors:

sodium isopentyl xanthate:                             BCF = 6.9

Very low values of: Experimental result of log Pow, estimated values of BAF (Bio-accumulation Factor) and BCF (Bio-concentration Factor) indicate that bio-accumulation of sodium isopentyl xanthate (CAS#2540-36-5) is unlikely.

Toxicity:

Predicted no effect concentration – PNEC = 0,47µg/dm3in fresh or marine water.

According to REACH Regulations (Annex XII) criteria sodium isopentyl xanthate (CAS# 2540-36-5) may be consider as very toxic for aquatic environment.