Registration Dossier
Registration Dossier
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EC number: 700-596-9 | CAS number: 14442-94-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The MLA returned a negative result both with and without metabolic activation.
The Ames test was negative therefore the test material was considered to be non-mutagenic.
The chromosome aberrations test was negative. The test material did not induce any statistically significant, dose-related increases in the frequency of cells with structural or numerical chromosome aberrations either in the presence or absence of a liver enzyme metabolising system or after various exposure times. The test material was therefore considered to be non-clastogenic to CHL cells in vitro.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
The MLA, Ames test and the chromosome aberration test were negative. Therefore, based on the evidence of the studies undertaken this substance is not classified at this level, Annex VII.
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