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EC number: 935-853-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Between 04 June 2009 and 17 August 2009.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to GLP and in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do no effect the quality of the relevant results
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Date of GLP inspection: 19/08/2008 Date of Signature on GLP certificate: 4/03/2009
- Type of method:
- other: HPLC screening method
- Media:
- other:
Test material
- Reference substance name:
- Reaction mass of 2-(3-ethylphenyl)oxirane and 2,2’-(1,3-phenylene)dioxirane and 2,2'-(1,4-phenylene)dioxirane
- EC Number:
- 935-853-6
- IUPAC Name:
- Reaction mass of 2-(3-ethylphenyl)oxirane and 2,2’-(1,3-phenylene)dioxirane and 2,2'-(1,4-phenylene)dioxirane
- Reference substance name:
- Reaction mass of bis(epoxyethyl) benzene and (ethylphenyl) oxirane
- IUPAC Name:
- Reaction mass of bis(epoxyethyl) benzene and (ethylphenyl) oxirane
- Reference substance name:
- DVBDO and EVBO (divinylbenzene dioxide and ethylvinylbenzene oxide)
- IUPAC Name:
- DVBDO and EVBO (divinylbenzene dioxide and ethylvinylbenzene oxide)
- Details on test material:
- - Name of test material (as cited in study report): Reaction mass of bis(epoxyethyl) benzene and (ethylphenyl) oxirane
- Substance type: Multiconstituent
- Physical state: clear extremely pale yellow liquid
- Analytical purity: 80 - 95%
- Impurities (identity and concentrations):
2-(4-ethylphenyl)oxirane : 6.4 %(w/w)
2-(4-ethenylphenyl)oxirane : 0.1% (w/w)
2-(3-ethenylphenyl)oxirane) : 1.4% (w/w)
- Composition of test material, percentage of components:
Oxirane, 2,2’-(1,3-phenylene)bis- : 53.0%
Oxirane, 2,2’-(1,4-phenylene)bis- : 27.0%
Oxirane, 2-(3-ethylphenyl)- : 13.0%
Oxirane, 2-(4-ethylphenyl)- : 7.0%
- Lot/batch No.: 200901317-17
- Stability under test conditions : decomposes above boiling temperature
- Storage condition of test material : approximately 4°C in the dark
Constituent 1
Constituent 2
Constituent 3
- Radiolabelling:
- no
Study design
- Test temperature:
- EXAMPLE: 40ºC
HPLC method
- Details on study design: HPLC method:
Preparation of sample solution:
Test material (0.0605 g) was diluted to 50 ml with acetonitrile.
Determination of retention time:
The sample, formamide and reference standard solutions were injected in duplicate using the following HPLC parameters:
HPLC System: Agilent Technologies 1200, incorporating autosampler and workstation
Column: Phenosphere Next CN 5µ (250 x 4.6 mm id)
Column temperature: 30 ºC
Mobile phase: methanol: water (55:45)
pH of mobile phase: 7.2
Flow-rate: 1 mL/min
UV detector wavelength: dead time and reference standards: 210 nm, sample: 220 nm
Injection volume: 10 µL
Construction of calibration curve:
A calibration curve was constructed from the retention time data of the formamide and reference standard solutions. The capacity factors (k) for the reference standards were calculated using Equation 8.1 (see below)
Adsorption coefficient of sample:
The capacity factor was calculated using Equation 8.1 (see below) and the log10 Koc value determined with reference to the calibration curve.
Calculation
The capacity factor was determined using Equation 8.1 (please see below).
EXAMPLE:
Batch equilibrium or other method
- Analytical monitoring:
- no
- Details on sampling:
- - Concentrations:
- Sampling interval:
- Sample storage before analysis:
Results and discussion
Adsorption coefficientopen allclose all
- Type:
- Koc
- Value:
- 64.4 - 318
- Type:
- log Koc
- Value:
- 1.81 - 2.5
Results: Batch equilibrium or other method
- Adsorption and desorption constants:
- Not applicable
- Recovery of test material:
- Not applicable
- Concentration of test substance at end of adsorption equilibration period:
- Not applicable
- Concentration of test substance at end of desorption equilibration period:
- Not applicable
- Transformation products:
- not measured
- Details on results (Batch equilibrium method):
- Not applicable.
- Statistics:
- None stated.
Any other information on results incl. tables
Calibration
The retention times of formamide and the retention times, capacity factors (k) and log10Kocvalues for the reference standards are shown in the two following tables:
Dead Time |
Retention Time (mins) |
Mean Retention Time (mins) |
|
Injection 1 |
Injection 2 |
||
Formamide |
3.518 |
3.494 |
3.506 |
Standard |
Retention Time (mins) |
Mean Retention Time (mins) |
Capacity Factor (k) |
Log10k |
Log10Koc |
|
Injection 1 |
Injection 2 |
|||||
Acetanilide |
4.254 |
4.258 |
4.256 |
0.214 |
-0.670 |
1.25 |
Phenol |
4.270 |
4.270 |
4.270 |
0.218 |
-0.662 |
1.32 |
Atrazine |
4.755 |
4.762 |
4.759 |
0.357 |
-0.447 |
1.81 |
Isoproturon |
5.171 |
5.179 |
5.175 |
0.476 |
-0.322 |
1.86 |
Triadimenol |
5.605 |
5.547 |
5.576 |
0.590 |
-0.229 |
2.40 |
Linuron |
6.464 |
6.462 |
6.463 |
0.843 |
-7.40 x 10-2 |
2.59 |
Naphthalene |
8.095 |
8.079 |
8.087 |
1.307 |
0.116 |
2.75 |
Endosulfan-diol |
6.330 |
6.345 |
6.338 |
0.808 |
-9.28 x 10-2 |
3.02 |
Fenthion |
10.728 |
10.686 |
10.707 |
2.054 |
0.313 |
3.31 |
a-Endosulfan |
11.056 |
11.054 |
11.055 |
2.153 |
0.333 |
4.09 |
Phenanthrene |
14.365 |
14.302 |
14.329 |
3.087 |
0.490 |
4.09 |
Diclofop-methyl |
13.372 |
13.373 |
13.373 |
2.814 |
0.449 |
4.20 |
DDT |
31.719 |
31.576 |
31.648 |
8.027 |
0.905 |
5.63 |
Adsorption coefficient of sample
The retention times, capacity factors and log10Kocvalues determined for the sample are shown in the following table:
Peak Number |
Injection |
Retention Time |
Capacity Factor |
Log10k |
Log10Koc |
Mean |
1 |
1 |
4.887 |
0.394 |
-0.405 |
1.81 |
1.81 |
2 |
4.891 |
0.395 |
-0.403 |
1.81 |
||
2 |
1 |
5.970 |
0.703 |
-0.153 |
2.50 |
2.50 |
2 |
5.976 |
0.705 |
-0.152 |
2.51 |
log10Kocrange: 1.81
to 2.50
Adsorption coefficient: 64.4 to 318
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The adsorption coefficient (Koc) of the test material has been determined to be 64.4 to 318, log10 Koc 1.81 to 2.50.
- Executive summary:
- The determination was carried out using the HPLC
screening method, Method C19 Adsorption Coefficient ofCommissionRegulation
(EC) No 440/2008 of 30 May 2008. The adsorption coefficient (Koc)
of the test material has been determined to be 64.4 to 318, log10Koc 1.81
to 2.50.
This is an indication that the substance is unlikely to adhere to soil particles in the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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