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Diss Factsheets
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EC number: 297-474-6 | CAS number: 93572-43-1 A complex combination of hydrocarbons obtained by refining of crude oil. It consists predominantly of aromatics, naphthenics and paraffinics and produces a finished oil with a viscosity of 120 SUS at 100°F (23cSt at 40°C).
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Study period:
- 1986
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study summary report
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- ROBUST SUMMARY OF INFORMATION ON LUBRICATING OIL BASESTOCKS
- Author:
- American Petroleum Institute
- Year:
- 2 003
- Bibliographic source:
- ROBUST SUMMARY OF INFORMATION ON LUBRICATING OIL BASESTOCKS pag 33
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Draize test
- Deviations:
- not specified
- Principles of method if other than guideline:
- 0.1 ml of undiluted test material was applied to the corneal surface of one eye of each of 9 rabbits, the other eye was untreated and served as control. After 20 to 30 seconds, the treated eyes of 3 rabbits were washed with lukewarm water for 1 minute. Eyes of the other 6 rabbits were not washed.
Readings of ocular lesions for all animals were made at 1, 24, 48, 72 hours and 7 days after treatment. Sodium fluorescein was used to aid in revealing possible corneal injury. - GLP compliance:
- not specified
Test material
- Reference substance name:
- Distillates (petroleum), hydrotreated light naphthenic
- EC Number:
- 265-156-6
- EC Name:
- Distillates (petroleum), hydrotreated light naphthenic
- Cas Number:
- 64742-53-6
- IUPAC Name:
- 64742-53-6
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- other: Only one eye was exposured, the other eye was untreated and served as control.
- Duration of treatment / exposure:
- 20 to 30 seconds
- Observation period (in vivo):
- 7 days
- Number of animals or in vitro replicates:
- 9
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: 1h
- Score:
- > 2 - < 2.7
- Max. score:
- 2.7
- Reversibility:
- not specified
- Remarks on result:
- other: There was no pain response during instillation of the test material and no corneal or iridial irritation was seen during the study.
Any other information on results incl. tables
There was no pain response during instillation of the test material and no corneal or iridial irritation was seen during the study. Any irritation that occurred had cleared by 48 hours.
The primary eye irritation scores for the first 48 hours of the study were as follows:
Period | Unwash eyes | Washed eyes |
1 hour | 2.7 | 2 |
24 hours | 0.3 | 0 |
48 hours | 0 | 0 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.