Registration Dossier
Registration Dossier
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EC number: 700-340-6 | CAS number: 76524-94-2
Endpoint summary
Administrative data
Description of key information
Oral rat fixed dose: LD50 > 2000 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
A high reliable study according to OECD guideline 420 was performed with 5 female Wistar rats under GLP conditions. The animals were treated with 2000 mg/kg bw of the test substance by gavage in a single dose. Clinical signs like ataxia, hunched posture, lethargy and ptosis were observed. The animals appeared normal for four hours or one day after dosing and no deaths occured. The LD50 was therefore set to be > 2000 mg/kg bw.
Justification for classification or non-classification
No mortalities occured in a fixed dose study at 2000 mg/kg bw, therefore the test substance was not classified according to DSD and CLP.
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