Registration Dossier
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Diss Factsheets
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EC number: 800-765-8 | CAS number: 1424149-03-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
BIODEGRADATION IN WATER: SCREENING TESTS
Test on Ready biodegradability
The registration substance was tested in a ready biodegradability test (OECD 301B, Closed Bottle Test). The inoculum was prepared according OECD 301C test guidleine from municipal activated sludge (4 different STPs), river water, lake water and estuary water The degradation rate based on O2 consumption reached a maxium of 53% at a test item concentration of 10 mg/L. Based on the degradation rate the registration substance is not readily biodegradable under the test conditions chosen.
Test on Inherent biodegradability
In an OECD 302B test the registration substance was inherent primary biodegradable, but not inherently biodegradable under the test conditions chosen. The maximum degradation rate of 57% was reached at day 21.
BIODEGRADATION: SIMULATION TESTS
SEWAGE TREATMENT PLANT
The registration substance was tested in an OECD 303A Sewage Treatment Plant Simulation Test over 37d using a test item concentration of 24.8 mg/L. After the run-in phase the test item was monitored over 17d using 24h composite samples and DOC Analysis. Based on these measurements a Biodegradation rate of 62% +/- 3% was determined. This biodegradation rate is in line with the degradation found in a ready and in an inherent test (see IUCLID Chapter 5.2.1).
SEDIMENT
Considering the full life cycle of the substance no direct exposure to sediment is expected.
Based on the Log Kow of 1.1 -1.6 at pH 7 (see IUCLID Chapter 4.7) the Exposure Modelling Program EUSES 2.1 calculates a low Koc of 10.4 L/kg (QSAR for organic acids) which corresponds to a Kd sediment of 0.5 L/kg (2% organic carbon) . Due to this very low sorption of the registration substance transfer from freshwater to sediment and thereby indirect exposure to sediment can be neglected. Therefore a simulation study on sediment biodegradation is not warranted.
SOIL
Considering the full life cycle of the substance no direct exposure to soil is expected.
Based on the Log Kow of 1.1 -1.6 at pH 7 (see IUCLID Chapter 4.7) the Exposure Modelling Program EUSES 2.1 calculates a low Koc of 10.4 L/kg (QSAR for organic acids) which corresponds to a Kd soil of 0.2 L/kg (2% organic carbon) and a Kd sewage sludge of 3.8 L/kg (37% organic carbon). Due to the very low sorption of the registration substance transfer from sewage sludge to agricultural soil via sludge amendment and thereby indirect exposure to soil can be neglected. Therefore a simulation study on soil biodegradation is not warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.