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Diss Factsheets
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EC number: 916-533-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
Description of key information
The melting point of the registered substance, Reaction mass of disodium N-coco acyl-L-glutamate and sodium N-coco acyl-L-glutamate, has been addressed based on read across to the following three analogues:
Sodium N-coco acyl-L-glutamate: Decomposition from 451 K, Walker (2008)
Sodium N-lauroyl-L-glutamate: Decomposition from 456 K, Walker (2008)
Sodium N-myristoyl-L-glutamate: Decomposition with melting from 465 to 504 K, Butler (2008)
All three studies were conducted in accordance with EU Method A.1.
Based on the read across data the registered substance is considered to melt with decomposition from 451 K, based on the lowest observed result.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 451 K
Additional information
The melting point of the registered substance has been addressed using read across to three structurally similar substances, provided as a weight of evidence.
Walker (2008a) determined the melting point of sodium N-coco acyl-L-glutamate using a modified capillary method/ melting temperatures devices with a liquid bath. Under the conditions of the study, the test material was determined to decompose at 458 K and 451 K in determinations 1 and 2, respectively. As a result of the slow, gradual colour change during decomposition, the onset temperatures could only be approximated. DSC testing indicated that the decomposition in the definitive (and preliminary) test was most likely due to thermal processes. During a metal block determination, the dark brown coloured powder (likely a mixture of test material and decomposition product(s)) started to liquefy from approximately 197 °C (470 K). Based on these results, the test material was determined to decompose from approximately 451 K.
Walker (2008b) determined the melting point of sodium N-lauroyl-L-glutamate using a modified capillary method/ melting temperatures devices with a liquid bath. Under the conditions of the study, the test material was determined to decompose at 458 K and 456 K in determinations 1 and 2, respectively. As a result of the low rate of colour change during decomposition, the onset temperatures could only be approximated. DSC testing indicated that the decomposition in the definitive (and preliminary) test was most likely due to thermal processes. During a metal block determination, the dark brown coloured powder (likely a mixture of test material and decomposition product(s)) started to liquefy from approximately 215 °C (488 K). Based on these results, the test material was determined to decompose from approximately 456 K.
Butler (2008) determined the melting point of sodium N-myristoyl-L-glutamate using a modified capillary method/ melting temperatures devices with a liquid bath. The test material went through several stages of physical change during the liquid bath test. Observations from determination 2 indicated the following; the test material became waxy at approximately 370 K, start of decomposition with melting indicated by discolouration and shrinkage started at approximately 465 K and end of decomposition with melting was at approximately 504 K.
A preliminary DSC test performed under air and nitrogen atmospheres indicated that no oxidative decomposition occurred. The thermograms showed an endotherm with a peak at approximately 90 °C corresponding to the test material becoming waxy and a broad endotherm starting at approximately 200 °C corresponding to decomposition with melting. The DSC thermogram was consistent with the observations made in the liquid bath experiment.
The test material was determined to decompose with melting from 465 to 504 K.
All three studies were performed under GLP and in line with the standardised guideline EU Method A.1, and were reported with sufficient detail to assess the reliability of the submitted data. Accordingly they were assigned a reliability score of 2 in line with Klimisch (1997).
Based on the read across data the registered substance is considered to melt with decomposition from 451 K, based on the lowest observed result.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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