Registration Dossier
Registration Dossier
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EC number: 700-869-2 | CAS number: -
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 7, 2011
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Solid Recovered Fuel (Municipal Solid Waste and similar wastes, processed)
- EC Number:
- 700-869-2
- Molecular formula:
- Not applicable
- IUPAC Name:
- Solid Recovered Fuel (Municipal Solid Waste and similar wastes, processed)
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Name: CarboNeXT
Physical state: fine powder
Colour: greyish
Storage conditions: at room temperature, protected from light
Constituent 1
Results and discussion
In vitro
Results
- Irritation parameter:
- cornea opacity score
- Value:
- 2.88
- Remarks on result:
- no indication of irritation
Any other information on results incl. tables
The eye irritancy potential of CarboNeXT was investigated in the bovine corneal opacity and permeability assay.
The test item was diluted with physiological saline 0.9% NaCl to gain a 20% concentration.
The following mean in vitro score was calculated: 2.88
Therefore the test item was classified as non irritant.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- According to the evalutation criteria the test item CarboNeXT is classified as non eye irritant.
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