Registration Dossier
Registration Dossier
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EC number: 249-881-5 | CAS number: 29820-13-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1979
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 979
- Report date:
- 1979
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- not applicable
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Calcium sulphidoacetate
- EC Number:
- 249-881-5
- EC Name:
- Calcium sulphidoacetate
- Cas Number:
- 29820-13-1
- Molecular formula:
- C2H4O2S.Ca x 3 H2O
- IUPAC Name:
- calcium 2-sulfanidylacetate
- Test material form:
- solid - liquid: suspension
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- CMC (carboxymethyl cellulose)
- Doses:
- 160, 200, 250, 320, 400, 450, 500 and 640 mg/kg
- No. of animals per sex per dose:
- 5
- Control animals:
- yes
Results and discussion
Effect levelsopen allclose all
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 352 mg/kg bw
- Based on:
- test mat.
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 245 mg/kg bw
- Based on:
- act. ingr.
- Clinical signs:
- other:
- Gross pathology:
- Exitus within 24 h, therefore no section conducted.
- Other findings:
- First exitus after 3 hours, last exitus after 24 hours.
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
- Conclusions:
- Toxic if swallowed. OECD GHS criteria Category 3 (50-300 mg/kg bw)
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