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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-fluoro-4-methyl-1,3,2-dioxaphospholane
- Cas Number:
- 16415-09-1
- Molecular formula:
- C3H6FO2P
- IUPAC Name:
- 2-fluoro-4-methyl-1,3,2-dioxaphospholane
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Inoculum used in this study was collected from 11 sites in Korea including 5 rivers(Gangjeongnaru, Mulgeum, Gwangju, Daejeon, Paldang), 2 industrial wastewater treatment plants(Dalseo, Yeosu) and 4 domestic sewage treatment plants(Dalseo, Gumi, Busan, Jungrang). Fresh samples collected from these sites at Setemper 2020 were incubated for over one month.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 10 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- BOD(Biochemical Oxygen Demand)
- Details on study design:
- The test was performed in the incubator to maintain a 25±1 ºC and reading of the BOD meter was recorded once a day. And the inoculum was treated at a concentration of about 10e+7~10e+8 cells/L.
After putting a sample in a BOD test bottle and treating activated sludge with a concentration of about 10e+7~10e+8 cells/L, the test was performed in an incubator to maintain a temperature of 25±1 ºC, and the reading of the BOD meter was recorded once a day.
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 18.6
- Sampling time:
- 28 d
- Remarks on result:
- other: not readily biodegradable
- Details on results:
- There was no environmental condition which might have affected the reliability of the test results and the test temperature was maintained at 24.4~25.8 ºC during the test by monitoring of datalogger.
BOD concentrations of the inoculum blank(bottle 6) for 28 days were 0.0~15.8 mg O2/L(Appendix 1).
These values were within the acceptable range(less than 60 mg O2/L for inoculums blank) specified by the OECD guideline.
The change of BOD concentrations for the test bottles was measured by BOD meter for 28 days. The difference of replicate value for the treatments(bottle 2, 3 and 4) at the end of the test was 3.9 % which was less than 20 % specified by the OECD guideline(Appendix 1).
The pH values at the end of BOD measurement were 7.41, 7.45 and 7.42 for test bottle 2, 3 and 4, respectively. These values were within the acceptable range(6.0~8.5 for pH) specified by the OECD guideline.
The percentage biodegradations of test substance, FCCA-04, based on BOD measurement were a range of 12.5~23.3 % and the average percentage biodegradation was calculated to be 18.6 % after 28 days.
This value was less than pass level of biodegradability specified by the guideline(Table 3).
After 28 days of the test, the residual amount of the test substance through analysis could not be calculated from the average concentration of the test substance group(test bottles 2, 3, 4) based on the concentration of the abiotic control(test bottle 1) because the test substance was not detected in all test bottles including the abiotic control.
BOD5 / COD results
- Results with reference substance:
- The percentage biodegradations of the reference compound(Sodium benzoate) were 68.8 % after 7 days and 65.3 % after 14 days and were within the acceptable range(greater than 40 % after 7 days and 65 % after 14 days) specified by the OECD guideline(Table 2).
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test substance could not be concluded as readily degradable by microorganisms in the aquatic environment. The average percentage biodegradation of the test substance by BOD measurement after 28 days was calculated to be 18.6 % which was less than pass level of biodegradability(60%) specified by the OECD guideline.
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