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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 January2018 - 19 July 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Method A5 Surface Tension of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 115 of the OECD Guidelines for Testing of Chemicals, 27
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: the critical micelle concentration (CMC) method was determined
Test material
- Test material form:
- semi-solid (amorphous): gel
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- ca. 5.54 mg/L
- Conc. based on:
- other: critical micelle concentration (CMC)
- Temp.:
- 20 °C
- pH:
- > 6.13 - <= 7.39
Any other information on results incl. tables
Refer to attached figure.
Line 1 (red) was generated from linear regression of 2 sample solution concentrations for which the surface tension was shown to be concentration dependent and Line 2 (green) was generated from linear regression of 5 sample solution concentrations for which the surface tension was observed to be essentially independent of concentration. The intersection of these two lines gave the critical micelle concentration and was calculated by solving the two equations:
Line 1 equation: y = -43.0x + 65.1 Line 2 equation: y = -1.29x + 34.2
The sample solutions at 0.3024 and 0.1008 mg/L were not used in generating the two lines.
The CMC was determined to be 5.54 mg/L.
Applicant's summary and conclusion
- Conclusions:
- The critical micelle concentration of the test item was determined to be 5.5 mg/L at 20.0 ± 0.5 °C.
- Executive summary:
Initially the water solubility method (EC A.6/OECD 105) was considered. A sample of 0.5191 g of test item and approximately 25 mL of purified water was shaken at 100 rpm for 10 minutes. After which, the sample was hazy with excess test item that had not dispersed. After vigorous shaking, the excess test item broke up and had foam on the surface. Clumps formed on standing and the solution was left clear. After allowing to stand overnight and then passing an aliquot through a 0.2 μm membrane filter, the solution was clear but with excess test item and a definitive Tyndall beam. This indicated that excess test item could not be completely removed from a solution as required by the water solubility method guidelines and that result would possibly vary with different loading rate. Therefore, the critical micelle concentration (CMC) method was attempted.
The CMC is an important characteristic of a surfactant. At low concentrations of surfactant, the surface tension of water is only slightly affected. Increasing the concentration but before reaching the CMC, the surface tension changes significantly. After reaching the CMC and above, the surface tension remains relatively constant or changes with a much more gradual slope.
Below the CMC, a surfactant is considered to be thermodynamically soluble in the water; whereas above the CMC, the solubility of a surfactant in water has been exceeded and the excess surfactant aggregates to form micelles. These micelles have significantly less effect on the surface tension of a solution and are considered not to be in solution. Thus, the water solubility of a surfactant may be expressed in terms of the CMC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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