Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Acute oral toxicity: similar to OECD TG 401: LD50 >5000 mg/kg bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
5 000 mg/kg bw

Additional information

Acute oral toxicity


The acute oral toxicity has been studied in a similar to OECD TG 401 test. The substance was administered at a dose of 5000 mg/kg bw to 5 male and 5 female SD rats and animals were observed for 14 days. No mortality and no clinical signs were observed. There were no treatment related necropsy findings. There were no adverse effects on bodyweight gain in animals of either sex except for one female losing 5 grams of weight between day 7 and 14. The acute oral toxicity (LD50) was determined to be >5000 mg/kg.

Justification for classification or non-classification

The substance does not have to be classified for Acute oral toxicity according to EU CLP (EC No. 1272/2008 and its amendments).