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Diss Factsheets
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EC number: 236-783-2 | CAS number: 13479-54-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
- Short-term toxicity to aquatic invertebrates: The EC50 (Daphnia magna) of the copper-glycine complex was determined to be 2.18 mg/L.
- Toxicity to aquatic algae and cyanobacteria: (Read-across) The geometric LC/EC50 mean across three pH-ranges in Pseudokirchneriella subcapitata was 0.139 mg Cu/L. This refers to 0.463 mg bis(glycinato)copper per Liter.
Additional information
Two independent studies have evaluated the toxicity of the copper-glycine complex to Daphnia magna. The results are in a close range: EC50 of 2.18 mg/L (Borgmann and Ralph, 1983) and LC50 of 2.129 mg/L (Khangarot et al. 1987). Both studies independently demonstrate that complexation of copper with glycine substantially reduces toxicity to Daphnia magna more than 20 -fold.
The result reported by Borgmann and Ralph (1983), EC50 2.18 mg/L in Daphnia magna, was chosen as key value for assessment because in the publication of Khangarot et al. (1987), no analytical monitoring was conducted.
The 72-h average EC50/LC50 of copper ions towards Pseudokirchneriella subcapitata was 0.139 mg Cu/L as derived from a data collection of the respective European Union Risk Assessment Report. This refers to 0.463 mg bis(glycinato)copper per Liter.
The test item is considered to be very toxic to aquatic life according to Regulation (EC) No 1272/2008 (CLP) and the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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