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Diss Factsheets
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EC number: 628-079-2 | CAS number: 3680-69-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From January 25, 2021 to February 23, 2021
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 17th July 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Batch number: 4419-190704
Purity: 99.3% - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): A fresh sample of activated sludge was collected from the aeration tank of Shenyang North Sewage Treatment Plant on the start day of the test.
- Preparation of inoculum for exposure: The inoculum was pretreated as follows: coarse particles were removed by filtration through a fine sieve and the sample was settled. After the supernatant was discarded, the sludge was washed twice with mineral medium and the concentrated sludge was suspended in mineral medium. 4 replicates of 10 mL suspended sludge was weighed and dried at 105oC for 1.5 hours and reweighed to calculate initial sludge concentration. The measured concentration of suspended sludge was 5.515 g/L as suspended solids (SS). The suspended sludge was prepared with mineral medium to yield a concentration of 4 g/L as suspended solids (SS) and keep the suspended sludge aerobic at 22.0oC ~ 23.5oC until the start of the test. On the day of the test 5 replicates of 10 mL suspended sludge was weighed and dried at 105C for 1.5 hours and reweighed to calculate initial sludge concentration. The measured concentration of suspended sludge was 3906 mg/L as suspended solids (SS).
- Initial cell/biomass concentration: 30 mg/L (as suspended solids (SS)) - Duration of test (contact time):
- 28 d
- Initial conc.:
- 89.72 mg/L
- Based on:
- test mat.
- Details on study design:
- TEST CONDITIONS
- Composition of medium: potassium dihydrogen orthophosphate, isodium hydrogen orthophosphate dihydrate, ammonium chloride, Calcium chloride dihydrate, magnesium sulfate heptahydrate, iron (III) chloride hexahydrate.
- Test temperature: 22oC±1oC
- Suspended solids concentration: 30 mg/L (as suspended solids (SS))
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: 250 mL flask
- Number of culture flasks/concentration: 2 replicates
- Measuring equipment: Oxygen uptake was measured by BOD analyzer.
CONTROL AND BLANK SYSTEM
- Inoculum blank: Test vessels containing only 250 mL inoculated mineral medium were prepared in duplicate and served as inoculum controls.
- Toxicity control: Toxicity control test vessel contained both test item and reference item. - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- Based on the percentage biodegradation expressed as average, the percentage biodegradation of test item after 28 days averaged 0.0% (2 replicates). The percentage degradation of the test item did not reach the pass level of 60% after 28 days of the test.
- Results with reference substance:
- Biodegradation of the reference substance (Sodium benzoate) reached 61.4% after 3 day and 17 hours, and was 78.1% after day 14, and 84.0% after day 28.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The percentage biodegradation of test item after 28 days averaged 0.0% (2 replicates). The test item is not readily biodegradable under the described test conditions.
- Executive summary:
The ready biodegradability test of the test item was conducted with unacclimatised sewage micro-organism by measuring oxygen consumption over a 28-day test period, according to OECD Guideline 301F under GLP.
The percentage biodegradation of test item after 28 days averaged 0.0% (2 replicates). The test item is not readily biodegradable under the described test conditions.
Reference
Description of key information
The ready biodegradability test of the test item was conducted with unacclimatised sewage micro-organism by measuring oxygen consumption over a 28-day test period, according to OECD Guideline 301F under GLP.
The percentage biodegradation of test item after 28 days averaged 0.0% (2 replicates). The test item is not readily biodegradable under the described test conditions.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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