Registration Dossier
Registration Dossier
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EC number: 203-996-7 | CAS number: 112-67-4
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to fish
Parent compound palmitoyl chloride: With high probability acutely not harmful to fish (96 -h LC50 = 145 mg/L).
Hydrolysis product palmitic acid: With high probability acutely not harmful to fish. No toxic effects within range of water solubility (96 -h LC50 > 6.9 mg/L).
Hydrolysis product HCl: Acutely toxic for fish (pH-dependent; 96 -h LC50 = 4.92 mg/L).
Long-term toxicity to fish
Not an information requirement for the registered tonnage band.
Short-term toxicity to aquatic invertebrates
Parent compound palmitoyl chloride: No data.
Hydrolysis product palmitic acid: With high probability acutely not harmful to aquatic invertebrates within range of water solubility (48 -h EC50 > 0.25 mg/L).
Hydrolysis product HCl: Acutely very toxic for aquatic invertebrates (pH dependent; 48 -h EC50 = 0.492 mg/L).
Long-term toxicity to aquatic invertebrates
Parent compound valeryl chloride: No data.
Hydrolysis product valeric acid: No toxic effect within range of water solubility (21 -d NOEC > 0.22 mg/L).
Hydrolysis product HCl: No data.
Toxicity to aquatic algae
Parent compound palmitoyl chloride: no data.
Hydrolysis product palmitic acid: With high probability acutely not harmful to algae within range of water solubility (72 -h ErC50 > 0.6 mg/L, 72 -h NOEC = 0.6 mg/L).
Hydrolysis product HCl: Acutely very toxic to aquatic algae (pH dependent; 72 -h ErC50 = 0.492 mg/L).
Toxicity to microorganisms
Parent compound palmitoyl chloride: No data.
Hydrolysis product palmitic acid: An inhibition of the degradation activity of activated sludge is not anticipated when the substance is introduced in appropriate low concentrations.
Hydrolysis product HCl: No data.
Additional information
Palmitoyl chloride hydrolyses very quickly to palmitic acid (CAS 57 -10 -3) and HCl (CAS 7647 -01 -0) (t1/2 < 5 min, see IUCLID Ch. 5.1.2). Therefore, the assessment is mainly based on the hydrolysis product palmitic acid.
Water solubility of palmitic acid (CAS 57 -10 -3) = 0.04 mg/L, at 25 °C, Robb 1966, PhysProp database of EPI Suite v4.11
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