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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
September - December, 2013.
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
Guideline study performed under GLP. All relevant validity criteria were met.
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23 March, 2006.
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
gas saturation method
Specific details on test material used for the study:
GR-50-1408 is the Givaudan identification code which was employed for ROSYFOLIA during the early, developmental and testing period.
Key result
Temp.:
20 °C
Vapour pressure:
0.5 Pa
Remarks on result:
other: Vapour Pressure derived from average of detected headspace concentrations of test item at 24, 28, 48 and 52 hours.

 


Headspace vapour concentrations of GR-50-1408 as found after an equilibration time of 24h, 28h, 48h and 52h are exposed in the below table.


 


The vapour pressure at 20°C was calculated from the average headspace concentration using the following equation:


p = W/V – RT/M


 


p is the vapour pressure in Pascal (Pa)


W is the mass of test substance in the aspirated volume (g)


V is the aspirated volume (volume of the burette) (m³)


R is the universal gas constant (8.314 J-mol-1-K-1)


T is the test temperature (K)


M is the molecular mass of the test substance (g mol-1)


 






































Equilibration time(h)



Headspace concentration (g/m³)



 



 



24



0.0426



28



0.0396



48



0.0446



52



0.0352



 



 



Average



0.0405


Conclusions:
The vapour pressure of the test material GR-50-1408 has been determined to be 0.5 Pa at 20°C using the Gas Saturation method.
Therefore vapour pressure of GR-50-1408: 0.5 Pa at 20°C.

Description of key information

The vapour pressure of the test material GR-50-1408 has been determined to be 0.5 Pa at 20°C using the Gas Saturation method.

Therefore vapour pressure of GR-50-1408: 0.5 Pa at 20°C.

Key value for chemical safety assessment

Vapour pressure:
0.5 Pa
at the temperature of:
20 °C

Additional information