Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 472-690-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 4 October - 2 November 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Version / remarks:
- December 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- 17 July 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): municipal sewage treatment plant 'Waterschap de Maaskant', 's-Hertogenbosch, The Netherlands
- Storage conditions: under continuous aeration
- Preparation of inoculum for exposure: before use, the sludge was allowed to settle (38 minutes) and the liquid was decanted for use as inoculum
- Concentration of sludge: 4.5 g suspended solids per litre of concentrated sludge
- Initial cell/biomass concentration: 10 ml/l of mineral medium - Duration of test (contact time):
- 28 d
- Initial conc.:
- 87.9 - 89 other: mg CO2/2L
- Based on:
- ThCO2
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- Test vessels: 2 litre all-glass brown coloured bottles
Stock solutions of mineral components:
A) 8.50 g KH2PO4, 21.75 g K2HPO4, 67.20 g Na2HPO4.12H2O, 0.50 g NH4Cl dissolved in Milli-Q water and made up to 1 litre, pH 7.4
B) 22.50 g MgSO4.7H2O dissolved in Milli-Q water and made up to 1 litre
C) 36.40 g CaCl2.2H2O dissolved in Milli-Q water and made up to 1 litre
D) 0.25 g FeCl3.6H2O dissolved in Milli-Q water and made up to 1 litre
Mineral medium: 1 litre mineral medium contains: 10 ml of solution A, 1 ml of solutions B, C and D, and Milli-RO water.
Barium hydroxide: 0.0125 M Ba(OH)2 stored in a sealed vessel to prevent absorption of CO2 from the air.
Synthetic air (CO2 < 1 ppm): a mixture of oxygen (21%) and nitrogen (79%) was passed through a bottle containing 0.5 - 1 litre 0.0125 M Ba(OH)2 solution to trap CO2 which might be present in small amounts. The synthetic air was sparged through the scrubbing solutions at a rate of 1-2 bubbles per second (ca. 30-100 ml/min).
Pre-incubation medium: mineral components, Milli-RO water (ca. 80% total volume) and inoculum (1% final volume) were added to each bottle. This mixture was aerated with synthetic air overnight to purge the system of CO2.
Type and number of bottles: 2 test suspension bottles (test substance + inoculum), 2 inoculum blank bottles (only inoculum), 1 positive control bottle (reference substance + inoculum), 1 toxicity control bottle (test substance + reference substance + inoculum)
Preparation: the test substance and positive control were added to the bottles containing the microbial organisms and mineral components. The volumes of suspensions were made up to 2 litres with Milli-RO water, resulting in the mineral medium described before. Three CO2-absorbers were connected in series to the exit air line of each test bottle. - Reference substance:
- acetic acid, sodium salt
- Test performance:
- All criteria for acceptability of the test were met, so the study was considered valid.
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 2 - 3
- Sampling time:
- 29 d
- Details on results:
- The relative degradation values calculated from the measurements performed during the test period revealed no significant degradation of the test substance.
In the toxicity control more than 25% degradation occurred within 14 days (34% based on ThCO2). Therefore, the test substance was assumed not to inhibit microbial activity.
Temperature ranged between 21.5 and 22.8°C, pH 7.1-7.5. - Results with reference substance:
- The degradation of sodium acetate after 29 days was 72%.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The substance was not readily biodegradable under the conditions of the modified Sturm test.
Reference
Description of key information
The substance was not readily biodegradable under the conditions of the modified Sturm test. Furthermore, in the toxicity control, more than 25% degradation occurred within 14 days. Therefore the test substance was assumed not to inhibit microbial activity.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.