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EC number: 500-013-6 | CAS number: 9004-78-8 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- yes
- Remarks:
- see 'principles of method if other than guideline'
- Principles of method if other than guideline:
- The study plan states that the test vessels should be incubated at 22±2°C for the duration of the study. However, over the course of the experimental period the temperature ranged from 19.9 – 21.3°C. Incubation temperatures dropped to a minimum of 19.9°C on days 2, 3, and 12 of the experimental period. As these were minor deviations limited in number and duration, these temperature excursions are not considered to have had any impact on the ultimate result of this study.
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum source: Cambridge STW, Cowley Road, Cambridge
Date of collection: 1st October 2019
Pre-treatment: Filtered (Whatman No. 54)
Temperature at start of test: 21.2°C
Concentration of inoculum: 1mL/L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 3 mg/L
- Based on:
- ThOD
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- acetic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 35
- Sampling time:
- 7 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 81
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 52
- Sampling time:
- 21 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 63
- Sampling time:
- 28 d
- Details on results:
- Phenol, ethoxylated achieved the requirements for a pass in this test (60% degradation relative to the ThOD value a maximum average degradation of 81% was recorded on day 14).
The OECD 301D guideline also requires that the test substance achieve a 14-day window, whereby 60% removal of the test substance is achieved within 14 days of 10% removal having been reached. As 81% removal was achieved within 14 days Phenol, ethoxylated passed this criteria.
All of the validity criteria were achieved over the course of the experimental period. Therefore, the final conclusion of this study is that Phenol, ethoxylated is readily biodegradable under the conditions of this test. - Results with reference substance:
- The guideline requires that the reference material degrades by at least 60% of its ThOD, and that the blank dissolved oxygen loss does not exceed 1.5mg/l after 28 days. Both of these criteria were satisfied for this test; a maximum average degradation value of 80% degradation of the sodium acetate was achieved on day 14, and the maximum blank DO loss was 1.03mg/l recorded on day 28. The difference in degradation values at the replicate extremes should also not exceed 20%, test item degradation values differed by 5% on day 28, reference replicates did not differ on day 14.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Phenol, ethoxylated is concluded to be ready biodegradable under the conditions of the test.
- Executive summary:
The biodegradation of Phenol, ethoxylated was evaluated in accordance with the OECD Testing Guideline 301D (Closed Bottle Test) and measured based on O2 consumption. The study was GLP-compliant.
The ThOD of the substance was calculated based on stuctural information. A ThOD of 2,145 mg O2 / g (corrected for concentration) was determined and used for the purpose of the study.
All of the validity criteria were achieved over the course of the experimental period. Phenol, ethoxylated achieved the requirements for a pass in this test (60% degradation relative to the ThOD value a maximum average degradation of 81% was recordedon day 14). The OECD 301D guideline also requires that the test substance achieve a 14-day window, whereby 60% removal of the test substance is achieved within 14 days of 10% removal having been reached. As 81% removal was achieved within 14 days Phenol, ethoxylated passed this criteria.
Phenol, ethoxylated is concluded to be ready biodegradable under the conditions of the test.
Reference
Description of key information
The biodegradation of Phenol, ethoxylated was evaluated in accordance with the OECD Testing Guideline 301D (Closed Bottle Test) and measured based on O2 consumption. The study was GLP-compliant.
The ThOD of the substance was calculated based on stuctural information. A ThOD of 2,145 mg O2 / g (corrected for concentration) was determined and used for the purpose of the study.
All of the validity criteria were achieved over the course of the experimental period. Therefore, the final conclusion of this study is that Phenol, ethoxylated is readily biodegradable under the conditions of this test.
Phenol, ethoxylated achieved the requirements for a pass in this test (60% degradation relative to the ThOD value a maximum average degradation of 81% was recorded on day 14). The OECD 301D guideline also requires that the test substance achieve a 14-day window, whereby 60% removal of the test substance is achieved within 14 days of 10% removal having been reached. As 81% removal was achieved within 14 days Phenol, ethoxylated passed this criteria.
Phenol, ethoxylated is concluded to be ready biodegradable under the conditions of the test.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
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