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EC number: 701-305-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- open test conditions
- Principles of method if other than guideline:
- Preparation of the water-accommodated fraction (WAF) as part of a toxicity study.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- Original name: Pitch, coal tar, high-temp., heat-treated [EC no. 310-162-7; CAS no. 121575-60-8] (CTPhtht)
- Water solubility:
- < 0.2 other: mg DOC/L
- Temp.:
- 20 °C
- pH:
- >= 7.7 - <= 8.2
- Remarks on result:
- other: estimated value from TOC measurements
- Details on results:
- Solubility data relate to loadings of 100 - 1000 mg pitch/L (see Remarks on results below).
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- As a summation parameter, TOC was measured rather than single PAHs.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- - Physical state: solid (here: applied as fine-granular powder < 180 µm)
- Density: 1.30 – 1.35 g/cm³ (20°C) (DIN 51 757)
- Stability under test conditions: WSF (water-soluble fraction): limited
- Storage condition of test material: room temperature, exclusion of light - Key result
- Water solubility:
- 0.242 mg/L
- Conc. based on:
- other: dissolved organic carbon (DOC)
- Loading of aqueous phase:
- 1 000 mg/L
- Temp.:
- 20 °C
- pH:
- 6.8
- Remarks on result:
- other: average over 3 time intervals (24, 48, and 72 h) measured in replicate samples
- Water solubility:
- 0.215 mg/L
- Conc. based on:
- other: dissolved organic carbon (DOC)
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 6.7
- Remarks on result:
- other: average at 72 h (replicate samples)
- Endpoint:
- water solubility
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
ANALOGUE APPROACH JUSTIFICATION
Coal-tar pitch, high temp. [CAS no. 65996-93-2] is the precursor of CTPhtht and used as analogue: similar structure and phys-chem. properties like the target substance, Pitch, coal tar, high-temp., < 1% 4- to 5-membered condensed ring aromatic hydrocarbons [EC no. 701-305-8] (CTPhtht). - Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- Read-across to preceding entry:
Source test material: pitch, coal tar (CTP)
Reference: NOACK 2011, water solubility - Specific details on test material used for the study:
- Original name: Pitch, coal tar, high-temp., heat-treated [EC no. 310-162-7; CAS no. 121575-60-8] (CTPhtht)
- Key result
- Water solubility:
- 0.242 mg/L
- Conc. based on:
- other: Dissolved Organic Carbon (DOC)
- Loading of aqueous phase:
- 1 000 mg/L
- Temp.:
- 22 °C
- pH:
- 6.8
- Remarks on result:
- other: average over 3 time intervals (24, 48, and 72 h) measured in replicate samples
- Key result
- Water solubility:
- 0.215 mg/L
- Conc. based on:
- other: Dissolved Organic Carbon (DOC)
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 72 h
- Temp.:
- 22 °C
- pH:
- 6.7
- Remarks on result:
- other: 72 h (replicate)
Referenceopen allclose all
Water solubility (as water-accommodated fraction) of CARBORES at 20 °C
in test medium (daphnia) at various loadings:
Note: Pitch-related values are in the range of background values and
hence are not precisely quantifiable by the method applied.
A. Main test
Loading [mg/L] |
||||
Control |
1000 |
|||
WAF [mg TOC/L] |
||||
24 h (stirring) |
0.9 |
0.5 |
Note: Values represent TOC including background.
B. Pre-test
Loading [mg/L] |
|||
Control |
100 |
1000 |
|
WAF [mg TOC/L] |
|||
24 h (stirring) |
0.6 |
0.5 |
0.7 |
Note: Values represent TOC including background.
Solubility Results for Pitch, coal tar, high temp(coal-tar pitch)
(Mean values of two replicates per time interval) (data taken from Table 4 of the report, modified)
Sample |
Carbon content [mg/L] |
|
||||
Dilution water1) |
0.732 |
Mean |
Mean over time (24, 48, 72 h)4) |
Mean over time (48, 72 h)4) |
Deviation (48, 72 h) [%] |
|
1000 mg/L |
No. 1 (24 h) |
0.320 |
0.2892) |
0.242 |
||
No. 2 (24 h) |
0.258 |
|||||
No. 1 (48 h) |
0.988 |
0.2043) |
0.218 |
14.5 |
||
No. 2 (48 h) |
0.883 |
|||||
No. 1 (72 h) |
0.930 |
0.2333) |
||||
No. 2 (72 h) |
1.000 |
|||||
100 mg/L |
No. 1 (72 h) |
0.186 |
0.2152) |
|
||
No. 2 (72 h) |
0.243 |
1) Dilution water for samples 48, 72 h at 1000 mg/L loading (measured 2010-11-15)
2) Mean values of replicates, dilution water carbon content not subtracted as dilution water carbon content
was 0 mg/L (measured 2010-11-12)
3) Mean values of replicates, dilution water carbon content subtracted (measured 2010-11-15)
4) The time average over 24,48, and 72 h was calculated, thus deviating from the study report in which only the average over 48 and 72 h has been quoted.
Description of key information
The water solubility of Pitch, coal tar, high-temp., < 1% 4- to 5-membered condensed ring aromatic hydrocarbons [EC no. 701-305-8] (CTPhtht) at 20 °C is estimated to be < 0.2 mg DOC/L at a loading of 1000 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 0.002 mg/L
- at the temperature of:
- 20 °C
Additional information
In an acute daphnia study with Pitch, coal tar, high-temp., < 1% 4- to 5-membered condensed ring aromatic hydrocarbons [EC no. 701-305-8] (CTPhtht), the measured TOC values at a loading of 1000 mg/L did not significantly differ from those of the control values. The relevant WAF is estimated to be < 0.2 mg/L (STZ 2007).
For coal-tar pitch, the structure analogous precursor compound, the mean TOC of the water-soluble fraction (WAF) was 0.24 mg/L at a loading of 1000 mg pitch/L. at 20 °C. A total of 0.8 to 1.4 µg/L was found in the WAF of a loading of 100 mg/L at 21 °C, related to the 16 EPA PAHs. It is conclusive to assume that CTPhtht [EC no. 701-305-8] will have a lower water solubility than coal-tar pitch, the precursor material [CAS No. 65996-93-2].
The solubility of benzo[a]pyrene (BaP) is adopted as representative parameter for single constituents that may be released and bioavailable.
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