Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 283-298-7 | CAS number: 84604-20-6 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Silybum marianum, Compositae.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Description of first aid measures
Inhalation: Allow the victim to rest. Assume fresh air breathing. Get medical advice/attention if you fell unwell.
Skin contact: Remove contaminated clothing for decontamination, remove from the bottom (as to not contaminated the face). Rinse the skin for at least 15 minutes with water. If skin irritation occurs: Get medical advice/attention.
Eye contact: Immediately rinse with clean water for 15-20 minutes. Avoid contaminating the healthy eye during rinsing. Consult and ophthalmologist if irritation persists.
Ingestion: Allow the victim to rest. Get medical advice/attention if you feel unwell.
Most important symptoms and effects, both acute and delayed
No additional information available.
Indication of any immediate medical attention and special treatment needed.
No additional information available.
Fire-fighting measures
Extinguishing media
Suitable Extinguishing media: Carbon dioxide, dry powder.
Special hazards arising from the substance or mixture
Hazard decomposition products in case of fire: COx, NOx
Advice for firefighters
Precautionary fire measures: Do not enter fire area without proper protective equipment: fire clothes, boots and individual respiratory protection.
Accidental release measures
Personal precautions, protective equipment and emergency procedures.
For non-emergency personnel: Ventilated spillage area.
For emergency responders: Delimit the discharge area. Discharges should be handled by trained cleaning personnel equipped with appropriate protection.
Environmental precautions
No special precautions.
Methods and materials for containment and cleaning up
Methods for cleaning up: Contain the discharges and collect them with absorbing material of the universal trade.
Handling and storage
Precautions for safe handling
Precautions for safe handling: Personnel should wear the appropriate protective equipment during use.
Hygiene measures: Wash hands thoroughly after handling.
Remove contaminated clothing.
Do not eat, drink or smoke in the handling room.
Inspect the individual protective equipment after handling.
No personal objects at the work station.
Avoid taking contaminated clothes home.
Change clothes systematically at coffee breaks or at meal times.
Conditions for safe storage, including incompatibilities
Recommended storage temperature: 5 degrees Celsius +/- 3 degrees Celsius
Specific end uses
Professional use only (manufacturing, storage, transport).
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- Not applicable - not regulated as dangerous goods.
Shipping information
- Proper shipping name and description:
- Not applicable.
- Chemical name:
- Not applicable.
- Language:
- English
- Labels:
- Not applicable.
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- Not applicable - not regulated as dangerous goods.
Shipping information
- Proper shipping name and description:
- Not applicable.
- Chemical name:
- Not applicable.
- Language:
- English
- Labels:
- Not applicable.
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- Not applicable - not regulated as dangerous goods.
Shipping information
- Proper shipping name and description:
- Not applicable.
- Chemical name:
- Not applicable.
- Labels:
- Not applicable.
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- Not applicable - not regulated as dangerous goods.
Shipping information
- Proper shipping name and description:
- Not applicable.
- Chemical name:
- Not applicable.
- Labels:
- Not applicable.
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Control parameters
No additional information available.
Exposure controls
Appropriate engineering controls:
Fumes detector. First-aid kit. Security instructions.
Hand protection: Wear suitable gloves resistant to chemical penetration.
Eye Protection: Chemical goggles or face shield.
Skin and body protection: Wear suitable protective clothing.
Respiratory protection: Respiratory mask P1 or FFP1 type
Thermal hazard protection: No additional information available.
Environmental exposure controls: No additional information available.
Stability and reactivity
Reactivity
No additional information available.
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No additional information available.
Conditions to avoid
Heat. Freezing.
Incompatible materials
No additional information available.
Hazardous decomposition products
COx. NOx
Disposal considerations
Waste treatment methods
Waste disposal recommendations: Dispose in a safe manner in accordance with local/national/regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.